Table 1.
Characteristics of SPS patients
| Patient no. | Sex | Number of SP | Number of AD | WHO criteria 2010 diagnosis* | Age at first polyp | History of CRC | History of extracolonic cancer | Smoking status |
|---|---|---|---|---|---|---|---|---|
| SPS1 | Female | >31 | >13 | 3 | 47 | No | Breast cancer | Current smoker |
| SPS2 | Female | 9 | 0 | 2 | 24 | No | No | Current smoker |
| SPS3 | Female | 30 | 5 | 3 | 47 | No | No | No smoker |
| SPS4 | Male | 17 | 2 | 1 | 57 | No | No | No smoker |
| SPS6 | Female | 10 | 9 | 1 | 51 | No | No | No smoker |
| SPS7 | Female | 1 | 0 | 2 | 39 | No | No | No smoker |
| SPS9 | Female | Multiple | 0 | 1 + 3 | 59 | Yes, 3×** | No | No smoker |
| SPS10 | Male | 70 | 12 | 1 + 3 | 60 | No | No | Former smoker |
| SPS11 | Male | >63 | 2 | 1 + 3 | 45 | No | No | Current smoker |
| SPS12 | Female | 46 | 7 | 3 | 54 | No | Hodgkin lymphoma | Former smoker |
| SPS13 | Male | 22 | 5 | 3 | 56 | No | No | Former smoker |
| SPS19 | Female | 63 | 1 | 1 + 3 | 52 | Yes, 1× | No | Former smoker |
| SPS20 | Male | >46 | 11 | 1 + 3 | 64 | No | No | Former smoker |
| SPS21 | Female | >10/multiple | >4 | 3 | 45 | No | No | Current smoker |
| SPS22 | Female | 61 | 0 | 1 + 3 | 60 | No | No | Current smoker |
| SPS24 | Male | 25 | 6 | 1 + 3 | 71 | No | No | Former smoker |
| SPS25 | Male | 44 | 0 | 1 + 3 | 42 | No | No | No smoker |
| SPS26 | Male | 22 | 17 | 3 | 49 | No | No | Former smoker |
| SPS27 | Male | 21 | 1 | 3 | 57 | No | Pancreatic IPMN | Former smoker |
| SPS28 | Female | >25 | 7 | 1 + 3 | 67 | No | Adrenal incidentaloma | Current smoker |
| SPS29 | Male | >63 | 2 | 1 + 3 | 59 | No | No | Current smoker |
| SPS32 | Male | 30 | 9 | 3 | 50 | No | No | Former smoker |
| SPS33 | Female | 32 | 4 | 1 + 3 | 77 | No | No | Current smoker |
| SPS34 | Male | >25 | 2 | 1 + 3 | 75 | Yes, 1× | No | Former smoker |
| SPS36 | Male | 32 | 17 | 1 + 3 | 61 | No | No | Current smoker |
| SPS37 | Female | 21 | 4 | 3 | 73 | No | Breast cancer | Former smoker |
SP, Serrated polyp; SPS, Serrated polyposis syndrome; AD, Conventional adenoma; CRC, Colorectal carcinoma.
*
According to the WHO criteria: 1, ≥5 SP proximal to the sigmoid (≥2 larger than 10 mm); 2, ≥1 SP proximal to the sigmoid + first‐degree relative with SPS; 3, >20 SP of any size, distributed over the entire colon.
**
SPS09: one medullar carcinoma, one poorly differentiated adenocarcinoma and one mucinous carcinoma.