Table 4.
Plasma sn‐1 alkyl or sn‐1 alkenyl phosphatidylethanolamine molecular species composition in men and women
| Proportion of total PtdEtn molecular species (%) | t‐Test | |||
|---|---|---|---|---|
| Molecular species | Men | Women | p‐Value | Adjusted p‐value |
| Alkyl molecular species | ||||
| PtdEtn O‐16:1_18:1 | 0.72 ± 0.09 | 0.92 ± 0.08 | 0.118 | 0.745 |
| PtdEtn O‐16:1_18:2 | 1.27 ± 0.14 | 1.50 ± 0.17 | 0.315 | 0.923 |
| PtdEtn O‐16:1_20:4 | 3.22 ± 0.43 | 5.47 ± 0.46 | 0.002 | 0.035 |
| PtdEtn O‐16:1_20:5 | 0.25 ± 0.04 | 0.35 ± 0.08 | 0.279 | 0.566 |
| PtdEtn O‐16:1_22:6 | 2.01 ± 0.28 | 2.60 ± 0.23 | 0.126 | 0.747 |
| PtdEtn O‐18:0_20:4 | 0.40 ± 0.05 | 0.55 ± 0.04 | 0.035 | 0.451 |
| PtdEtn O‐18:1_18:1 | 0.75 ± 0.11 | 0.81 ± 0.06 | 0.643 | 0.994 |
| PtdEtn O‐18:1_18:2 | 3.29 ± 0.41 | 3.17 ± 0.31 | 0.834 | 0.993 |
| PtdEtn O‐18:1_20:3 | 0.98 ± 0.14 | 1.30 ± 0.04 | 0.041 | 0.515 |
| PtdEtn O‐18:1_20:4 | 5.95 ± 0.90 | 7.68 ± 0.49 | 0.111 | 0.739 |
| PtdEtn O‐18:1_20:5 | 0.58 ± 0.10 | 0.83 ± 0.07 | 0.056 | 0.565 |
| PtdEtn O‐18:1_22:4 | 0.07 ± 0.01 | 0.31 ± 0.10 | 0.041 | 0.432 |
| PtdEtn O‐18:1_22:5 | 1.01 ± 0.12 | 1.28 ± 0.05 | 0.065 | 0.566 |
| PtdEtn O‐18:1_22:6 | 2.31 ± 0.35 | 2.49 ± 0.26 | 0.686 | 0.994 |
| PtdEtn O‐18:2_18:2 | 1.54 ± 0.15 | 1.80 ± 0.17 | 0.275 | 0.924 |
| PtdEtn O‐18:2_20:4 | 4.01 ± 0.36 | 5.48 ± 0.41 | 0.014 | 0.025 |
| PtdEtn O‐18:2_20:5 | 0.67 ± 0.05 | 0.80 ± 0.05 | 0.079 | 0.657 |
| PtdEtn O‐18:2_22:6 | 1.19 ± 0.08 | 1.41 ± 0.12 | 0.161 | 0.788 |
| PtdEtn O‐20:1_18:2 | 0.30 ± 0.03 | 0.30 ± 0.04 | 0.966 | 0.994 |
| PtdEtn O‐20:1_20:4 | 0.23 ± 0.03 | 0.36 ± 0.06 | 0.055 | 0.992 |
| PtdEtn O‐20:1_22:6 | 0.09 ± 0.02 | 0.10 ± 0.01 | 0.745 | 0.997 |
| Total | 30.83 ± 2.99 | 39.51 ± 1.32 | 0.021 | 0.991 |
| Alkenyl molecular species | ||||
| PtdEtn P‐16:0_18:1 | 1.06 ± 0.17 | 0.63 ± 0.08 | 0.041 | >0.999 |
| PtdEtn P‐16:0_18:2 | 2.73 ± 0.30 | 1.92 ± 0.21 | 0.040 | >0.999 |
| PtdEtn P‐16:0_20:4 | 8.28 ± 0.73 | 8.20 ± 0.51 | 0.931 | >0.999 |
| PtdEtn P‐16:0_22:6 | 4.61 ± 0.36 | 3.88 ± 0.25 | 0.114 | >0.999 |
| PtdEtn P‐16:0_22:6 | 1.17 ± 0.21 | 1.09 ± 0.24 | 0.816 | >0.999 |
| PtdEtn P‐18:0_18:1 | 0.95 ± 0.17 | 0.60 ± 0.08 | 0.098 | >0.999 |
| PtdEtn P‐18:0_18:2 | 4.05 ± 0.48 | 2.67 ± 0.32 | 0.029 | >0.999 |
| PtdEtn P‐18:0_20:4 | 9.70 ± 1.28 | 7.73 ± 0.81 | 0.214 | >0.999 |
| PtdEtn P‐18:0_20:5 | 0.77 ± 0.07 | 0.57 ± 0.07 | 0.071 | >0.999 |
| PtdEtn P‐18:0_22:6 | 3.41 ± 0.48 | 2.34 ± 0.30 | 0.077 | >0.999 |
| PtdEtn P‐18:1_18:2 | 2.81 ± 0.26 | 2.05 ± 0.18 | 0.028 | >0.999 |
| PtdEtn P‐18:1_20:4 | 10.11 ± 0.78 | 8.56 ± 0.39 | 0.100 | >0.999 |
| Total | 52.63 ± 4.29 | 42.34 ± 1.11 | 0.042 | >0.999 |
Values are mean ± SEM (n = 10 per sex) proportions of individual molecular species in total plasma PtdEtn (sn‐1 fatty acid / sn‐2 fatty acid). Comparisons of means between sexes were by Student's unpaired t‐test with adjustment for multiple testing using the Holm‐Šídák method. Molecular species are ranked by increasing number of carbons and degree of unsaturation of the sn‐1 fatty acid.