TABLE 3.
Logistic regression analysis assessing the impact of sex, level of education and presence of APOE ε4 allele(s) on the significant outcomes in baseline GDS scores between cognitive impairment, CERAD score and Braak stage groups
Cognitive impairment at death | CERAD score | Braak stage | |||||||
---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p value | OR | 95% CI | p value | OR | 95% CI | p value | |
Baseline GDS score | 1.08 | 0.98–1.18 | 0.104 | 1.08 | 0.99–1.17 | 0.094 | 1.09 | 1.00–1.18 | 0.060 |
Sex | 1.39 | 0.44–4.36 | 0.575 | 1.51 | 0.56–4.02 | 0.413 | 0.96 | 0.35–2.63 | 0.941 |
Education | 1.00 | 0.87–1.14 | 0.946 | 0.95 | 0.85–1.07 | 0.429 | 0.97 | 0.86–1.09 | 0.599 |
Presence of APOE ε4 | 2.50 | 0.94–6.65 | 0.067 | 2.98 | 1.17–7.60 | 0.023 | 3.16 | 1.24–8.05 | 0.016 |
Note: Bold indicates significant difference.
Abbreviations: CI, confidence interval; CERAD, Consortium to Establish a Registry for Alzheimer’s Disease; GDS, Geriatric Depression Scale; OR, odds ratio.