Fig. 6.

Colloidal particles as pathogens of arteriosclerosis

Two distinct forms of arteriosclerosis, atherosclerosis and vascular calcification, can be viewed collectively to be caused by mistargeting of circulating colloidal particles (lipoproteins and CPPs) containing insoluble materials (lipids and calcium–phosphate) to arterial walls. White circles, amorphous calcium–phosphate; black circles, crystalline calcium–phosphate; gray circles, fetuin-A; yellow circles, triglyceride; orange circles, cholesterol; blue circles, apoproteins.