TABLE 4.

False negative (FN) discordant results of ClearLLab to LDT

Specimen type	ClearLLab 10C result	LDT result	Comments
PB	No abnormal phenotype	B‐cell—non‐Hodgkin lymphoma, B‐cell type, NOS	Small B cell population CD5‐CD10‐with kappa light chain excess
BM	No abnormal phenotype	B‐cell—plasma cell myeloma	Abnormal population < 1%
BM	No abnormal phenotype	B‐cell—plasma cell myeloma	Abnormal population < 1%
PB	No abnormal phenotype	B‐cell—plasma cell myeloma	Poor viability sample. Surface light chain negative, intracellular positive
BM	No abnormal phenotype	B‐cell—plasma cell myeloma	Lack of marker(s) in ClearLLab 10C panel
BM	No abnormal phenotype	B‐cell—plasma cell myeloma	Abnormal population < 1%
BM	No abnormal phenotype	B‐cell—plasma cell myeloma	Abnormal population < 1%
BM	No abnormal phenotype	B‐cell—plasma cell myeloma	Small plasma cell population surface light chain negative, intracellular positive
BM	No abnormal phenotype	Other—other interpretation	Unable to discern malignancy: Abnormal phenotype (1.6%): Dim45+ 34+ 33+ 117+ 56± 7±
PB	No abnormal phenotype	T/NK‐cell—adult T‐cell leukemia/lymphoma	Unable to discern disease state without more clinical information
BM	No abnormal phenotype	T/NK‐cell—T‐cell large granular lymphocytic leukemia	Unable to discern disease state without more clinical information
PB	No abnormal phenotype	T/NK‐cell—T‐cell large granular lymphocytic leukemia	Unable to discern disease state without more clinical information

Abbreviation: BM, bone marrow; LDT, laboratory developed test; PB, peripheral whole blood.