Table 3:

Knowledge gaps related to maternal stroke

1.	Mechanisms of maternal stroke
	A. Understanding mechanisms related to known risk factors including HDP, migraine and infections
	B. Identification of other risk factors.
2.	Development and validation of risk prediction tools to identify women who are at increased risk for maternal stroke.
3.	Consideration of enrollment of pregnant and post-partum in future randomized controlled trials of therapies for acute ischemic stroke.
4.	Risk factor control strategies, including individualized blood pressure goals, prenatal care plan and preventive approaches for high-risk groups and racial groups.
5.	Investigating the impact of aggressive blood pressure control in HDP on the prevention of maternal stroke.
6.	Need for large-scale studies to evaluate the risk of stroke recurrence in women with maternal stroke, especially hemorrhagic stroke.

HDP= hypertensive disorders of pregnancy