Table 3.
Tumor Characteristics
| Variable | Overall, N = 12,544 (%) | No Reconstruction, n = 11,237 (%) | Reconstruction, N = 1307 (%) | P |
|---|---|---|---|---|
| Grade | 0.25 | |||
| 1 | 317 (2.5) | 293 (2.6) | 24 (1.8) | |
| 2 | 3266 (26) | 2902 (25.8) | 364 (27.9) | |
| 3 | 7279 (58) | 6533 (58.1) | 746 (57.1) | |
| 4 | 131 (1) | 120 (1.1) | 11 (0.8) | |
| Unknown | 1551 (12.4) | 1389 (12.4) | 162 (12.4) | |
| The American Joint Committee on Cancer stage | <0.001 | |||
| 1 | 832 (6.6) | 704 (6.3) | 128 (9.8) | |
| 2 | 1381 (11.0) | 1206 (10.7) | 175 (13.4) | |
| 3 | 10,331 (82.4) | 9327 (83) | 1004 (76.8) | |
| IBC diagnosis | <0.001 | |||
| Clinical | 8408 (67.0) | 7471 (66.5) | 937 (71.7) | |
| Pathology | 1688 (13.5) | 1533 (13.6) | 155 (11.9) | |
| Both | 2448 (19.5) | 2233 (19.9) | 215 (16.4) | |
| Tumor size | 0.23 | |||
| ≤20 mm | 1522 (12.1) | 1372 (12.2) | 150 (11.5) | |
| 21–50 mm | 3173 (25.3) | 2857 (25.4) | 316 (24.2) | |
| >50 mm | 3831 (30.5) | 3400 (30.3) | 431 (33.0) | |
| Unknown | 4018 (32) | 3608 (32.1) | 410 (31.4) | |
| Pathologic N stage | <0.001 | |||
| N0 (0 nodes) | 2622 (20.9) | 2291 (20.4) | 331 (25.3) | |
| N1 (1–3) | 3166 (25.2) | 2823 (25.1) | 343 (26.2) | |
| N2 (4–9) | 1300 (10.4) | 1166 (10.4) | 134 (10.3) | |
| N3 (≥10) | 4095 (32.6) | 3727 (33.2) | 368 (28.2) | |
| None examined | 819 (6.5) | 748 (6.7) | 71 (5.4) | |
| Unknown | 541 (4.3) | 481 (4.3) | 60 (4.6) | |
| Estrogen receptor status | 0.63 | |||
| Negative/borderline | 5662 (45.1) | 5088 (45.3) | 574 (43.9) | |
| Positive | 6541 (52.1) | 5843 (52.0) | 698 (53.4) | |
| Missing | 341 (2.7) | 306 (2.7) | 35 (2.7) | |
| Progesterone receptor status | 0.36 | |||
| Negative/borderline | 7102 (56.6) | 6343 (56.4) | 711 (54.4) | |
| Positive | 5097 (40.6) | 4542 (40.4) | 555 (42.5) | |
| Missing | 345 (2.8) | 352 (3.1) | 41 (3.1) | |
| HER2 receptor status* | 0.58 | |||
| Negative or borderline | 4476 (65.1) | 3936 (65.3) | 540 (63.8) | |
| Positive | 2219 (32.3) | 1933 (32.1) | 286 (33.8) | |
| Missing | 177 (2.6) | 157 (2.6) | 20 (2.4) | |
| Overall ER/PR status | 0.71 | |||
| ER−, PR− incl borderline | 5374 (42.8) | 4827 (43.0) | 547 (41.9) | |
| ER+ and/or PR+ | 6824 (54.4) | 6099 (54.3) | 725 (55.5) | |
| Missing | 346 (2.8) | 311 (2.8) | 35 (2.7) |
*HER2 receptor status collected by NCDB starting in 2010.
ER, estrogen receptor; PR, progesterone receptor.