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Ileal resections from B2 patients (a, hematoxylin and eosin [H&E]) showed lesser inflammation when compared with B3 patients (b, H&E; large superficial ulcer). Both specimens from B2 (c, Masson trichrome [MT]) and B3 (d, MT) patients showed prominent fibrosis. Granulomatous inflammation with giant cell (a, asterisk and inset). Hyperplastic and splayed muscularis mucosae, dissected by fibrosis (c, asterisk and inset).
