Table 3.
T cell number and proinflammatory cytokines of 127 children or adolescence with COVID-19. Values are medians (interquartile ranges) unless stated otherwise.
| Total | Mild | Moderate | Severe and Critical | |
|---|---|---|---|---|
| CD3+T cell proportion (38.56–70.06%) | 68.09 [63.61–72.95] | 69.36 [63.72–73.28] | 67.33 [62.96–71.09] | 70.49 [66.87–72.35] |
| CD3+T cell number (805–4459cell/L) | 2073 [1675–2779] | 1955 [1561–2391] | 2231 [1840–3230] | 2280 [1717–2644] |
| CD3+CD4+T cell proportion (14.21%−36.99%) | 35.81 [30.78–39.19] | 35.12 [30.52–39.03] | 35.90 [32.11–44.00] | 35.89 [33.24–37.03] |
| CD3+CD4+T cell number (345–2350cell/L) | 1012 [669–1569] | 911 [669–1120] | 1103 [739–1942] | 1010 [839–1391] |
| CD3+CD8+T cell proportion (13.24%−38.53%) | 27.52 [21.84–31.49] | 29.27 [25.93–31.49] | 25.00 [19.48–28.89] | 28.32 [26.32–31.15] |
| CD3+CD8+T cell number (314–2080cell/L) | 743 [556–1022] | 743 [556–977] | 806 [556–1200] | 1022 [692–1220] |
| Natural killer proportion (7.92%−33.99%) | 9.97 [5.71–14.59] | 9.87 [5.66–13.32] | 10.81 [5.97–15.12] | 11.80 [6.79–14.62] |
| Natural killer cell number (210–1514cell/L) | 316 [187–470] | 261 [150–471] | 370 [236–470] | 225 [182–417] |
| Lymphocyte (25%−40%) | 18.15 [15.35–22.61] | 19.05 [15.60–20.91] | 17.43 [13.41–23.34] | 16.50 [14.43–19.14] |
| CD19+B cell number (240–1317 cell/L) | 557 [372–822] | 515 [374–661] | 654 [364–950] | 528 [450–649] |
| CD4+/CD8+T ratio (0.96–2.05) | 1.34 [1.09–1.78] | 1.33 [1.06–1.59] | 1.47 [1.14–1.95] | 1.21 [1.16–1.34] |
| CD4+CD25+T cell proportion (%) | 4.93 [3.64–5.70] | 5.13 [4.19–5.62] | 4.31 [3.36–6.18] | 5.15 [3.74–6.73] |
| Human IL-2 (0–11.4pg/ml) | 1.43 [1.21–1.67] | 1.32 [1.18–1.56] | 1.50 [1.34–1.70] | 1.54 [1.33–1.68] |
| Human IL-4 (0–12.9pg/ml) | 2.68 [2.07–3.33] | 2.52 [2.03–3.11] | 2.74 [2.23–3.34] | 2.83 [2.55–3.42] |
| Human IL-6 (0–20.9pg/ml) | 3.98 [3.04–5.66] | 3.79 [2.95–4.97] | 4.17 [3.19–7.34] | 3.17 [2.68–3.59] |
| Human IL-10 (0–5.9pg/ml) | 3.50 [3.05–4.61] | 3.26 [2.88–3.89] | 4.01 [3.32–5.66] | 3.26 [3.05–4.13] |
| Human TNF-α (0–5.5pg/ml) | 1.62 [1.26–2.23] | 1.52 [1.19–1.82] | 1.78 [1.31–2.36] | 1.76 [1.5–2.39] |
| Human IFN-γ (0–17.3pg/ml) | 2.87 [2.23–3.91] | 2.87 [2.12–4.05] | 2.94 [2.38–3.89] | 2.78 [1.85–3.01] |