Table 2.
Adjusted hazard ratios (95% CI) for the final models for myeloma
| Variable | FBC model,a | All-test model,b |
|---|---|---|
| HR (95% CI) | HR (95% CI) | |
| Demographics | ||
| Female | 0.45 (0.37 to 0.54) | 0.48 (0.39 to 0.58) |
| Agec | FP (0.5, 0.5) | FP (0.5, 0.5) |
|
| ||
| Symptoms | ||
| Back pain | 2.37 (1.89 to 2.98) | 2.46 (1.96 to 3.10) |
| Chest pain | 1.76 (1.33 to 2.33) | 1.85 (1.39 to 2.45) |
| Rib pain | 2.94 (1.46 to 5.99) | 2.81 (1.38 to 5.72) |
| Nosebleeds | 2.26 (1.32 to 3.85) | 2.11 (1.23 to 3.61) |
|
| ||
| FBC | ||
| Haemoglobinc | FP (3, 3) | FP (3, 3) |
| White cell countc | FP (−2, −2) | FP (−2, −2) |
| Plateletsc | FP (−1, −0.5) | FP (−0.5, 0) |
| MCVc | FP (3, 3) | FP (3, 3) |
|
| ||
| Other tests | ||
| ESR | NA | 1.03 (1.03 to 10.33) |
| Calciumc | NA | FP (−1) |
a
FBC model contains a single FBC.
b
All-test model contains a single FBC, plus ESR and calcium.
c
Numerals in parenthesis represent the transformations used. CI = confidence interval. ESR = erythrocyte sedimentation rate.
FBC = full blood count. FP = fractional polynomials. HR = hazard ratio. MCV = mean corpuscular volume. NA = not applicable.