Table 2. Diagnosis of subjects in the high acuity cohort separated into those with high ISI (Red Band) and those with low ISI (Green Band).

Green Band (ISI 0.1–5.4) N = 195		Red Band (ISI 6.8–10.0) N = 59
Congestive Heart Failure/ Chest Pain/Atrial Fibrillation	54 (27.7%)	Sepsis	50 (84.7%)
Chronic Respiratory Disease/COPD	39 (20.0%)	Non-infectious Severe Immune Response (flare of Ulcerative Colitis, Rheumatoid Arthritis Pericarditis, Sarcoidosis)	3 (5.1%)
Abdominal Pain/GI Bleed/Volume Depletion	19 (9.7%)	Infection with Chronic/Direct Organ Dysfunction	2 (3.4%)
Complications of Diabetes	16 (8.2%)	Cardiac Arrest/Emergency Heart Failure	2 (3.4%)
Infection without Organ Dysfunction	14 (7.2%)	Other	2 (3.4%)
Alcohol/Substance Abuse	11 (5.6%)
Chronic Kidney Disease/ESRD	10 (5.1%)
Encephalopathy/seizures	10 (5.1%)
Sepsis	10 (5.1%)
Chronic liver Disease	4 (2.1%)
Direct Limb Injury/Fall	4 (2.1%)
Other	4 (2.1%)