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. 2021 Apr 15;16(4):e0247699. doi: 10.1371/journal.pone.0247699

Table 4. Measures of associations and p-value (or 95% confidence interval) for 10μg/m3 increase in concentrations of air pollutants by trimesters of pregnancy from regression models (defined as model 1 in §Material and methods) adjusted for individual covariates for boys.

BOYS
Birth weight Low birth weight Term low birth weight
Air pollutants Window of exposure β p-value OR [CI95%] OR [CI95%]
NO2 Entire pregnancy -2.6 0.261 1.07 [0.99;1.015] 1.05 [0.97;1.17]
T1 0.2 0.933 1.05 [0.98;1.13] 1.05 [0.97;1.14]
T2 -2.6 0.212 0.97 [0.89;1.04] 0.93 [0.85;1.02]
T3 0.3 0.859 1.07 [1.00;1.14]3 1.10 [1.02;1.19]5
PM10 Entire pregnancy -15.4 0.0341 1.23 [0.99;1.6] 1.24 [0.93;1.72]
T1 -9.2 0.0402 1.15 [0.99;1.37] 1.11 [0.91;1.36]
T2 -2.7 0.504 0.98 [0.85;1.14] 1.0 [0.83;1.20]
T3 -5.4 0.220 1.17 [1.01;1.32] 4 1.19 [1.01;1.39]6

Adjusted on: maternal age, gestational age, woman’s primary maternity (yes or no), and maternity classification (class I: low risk, class II: moderate risk and class III: high risk).

1: Controlling the False discovery rate (FDR) at α = 0.05 following the method of Benjamini & Hochberg [18], FDR α-risk = 0.007;

2: FDR α-risk = 0.009;

3FDR α-risk = 0.01;

4FDR α-risk = 0.006;

5FDR α-risk = 0.001;

6FDR α-risk = 0.01 [18].

Bold character presents significant result at 5%. Bold and italic character presents significant result at FDR-risk; Ref: referent value. β corresponds to regression coefficient of a linear regression; OR: Odds Ratio. NO2: Nitrogen dioxide. PM10: Particulate matter < 10 μm in aerodynamic diameter.