FIGURE 1.

(A) Schematic illustration of MC1R-avid radiolabeled α-MSH peptide to detect B16/F1 flank melanoma (T) and B16/F10 pulmonary metastatic melanoma (Mets) in mice and melanoma metastases in a melanoma patient. BM, LM, CM, and IM represent melanoma metastases in brain, lung, connective tissue, and intestines, respectively. (B) Representative α-MSH peptides. (Human and animal images reprinted with permission of 5, 19, and 20.)