Table 4.
Associations between underlying conditions and mortality among those who were hospitalised from COVID-19 within the study subset (n=2,811).
| Risk factor | Hospitalised and alive (n=2119) | Hospitalised and died (n=692) | Unadjusted OR (95% CI) | Adjusted OR for age1 (95% CI) | Adjusted OR2 (95% CI) |
|---|---|---|---|---|---|
|
Gender Male Female (reference) |
1195 924 |
421 (26.05%) 271 (21.68%) |
1.20 (1.01, 1.43) |
1.34 (1.11, 1.65)* |
1.38 (1.12, 1.71)* |
|
Chronic heart disease Yes No |
649 1470 |
342 (34.51%) 350 (19.23%) |
2.21 (1.86, 2.64) |
1.30 (1.07, 1.58)* |
1.23 (0.99, 1.54) |
|
Chronic neurological condition Yes No |
198 1921 |
160 (44.69%) 532 (21.69%) |
2.92 (2.32, 3.67) |
1.75 (1.37, 2.24)*** |
1.37 (1.04, 1.81)* |
|
Chronic respiratory disease Yes No |
391 1728 |
167 (29.93%) 525 (23.30%) |
1.41 (1.14, 1.73) |
1.16 (0.92, 1.45) |
1.19 (0.92, 1.53) |
|
Chronic kidney disease Yes No |
157 1962 |
120 (43.32%) 572 (22.57%) |
2.62 (2.03, 3.38) |
1.91 (1.45, 2.53)*** |
1.75 (1.29, 2.38)** |
|
Chronic liver disease Yes No |
47 2072 |
21 (30.88%) 671 (24.46%) |
1.38 (0.82, 2.33) |
1.50 (0.86, 2.63) |
1.30 (0.72, 2.34) |
|
Asthma (requiring medication) Yes No |
138 1981 |
20 (12.66%) 672 (25.33%) |
0.43 (0.27, 0.69) |
0.52 (0.31, 0.87)* |
0.49 (0.28, 0.85)* |
|
Immunodeficiency incl. HIV Yes No |
85 2034 |
28 (24.78%) 664 (24.61%) |
1.01 (0.65, 1.56) |
1.24 (0.77, 2.00) |
0.91 (0.54, 1.55) |
|
Diabetes Yes No |
333 1786 |
125 (27.29%) 567 (24.10%) |
1.18 (0.94, 1.48) |
1.00 (0.78, 1.27) |
0.84 (0.64, 1.10) |
|
BMI ≥40kg/m2 Yes No |
104 2015 |
30 (22.39%) 662(24.73%) |
0.88 (0.58, 1.33) |
1.81 (1.14, 2.86)* |
2.19 (1.34, 3.56)* |
|
Cancer / malignancy Yes No |
203 1916 |
148 (42.17%) 544 (22.11%) |
2.57 (2.04, 3.24) |
2.11 (1.63, 2.71)*** |
2.15 (1.63, 2.83)*** |
|
Other comorbidity Yes No |
699 1420 |
405 (36.68%) 287 (16.81%) |
2.87 (2.40, 3.42) |
2.30 (1.90, 2.79)*** |
2.05 (1.65, 2.55)*** |
|
Comorbidity unknown$ Yes No |
120 1999 |
39 (24.53%) 653 (24.62%) |
1.00 (0.69, 1.44) |
0.62 (0.41, 0.92)* |
0.96 (0.59, 1.58) |
|
Residential care facility Yes No |
83 2036 |
150 (62.38%) 542 (21.02%) |
6.79 (5.11, 9.02) |
3.80 (2.79, 5.17)*** |
5.02 (3.46, 7.30)*** |
a
1Adjusted OR, adjusted for age (linear)
2Adjusted OR, adjusted for age (linear), chronic heart disease, chronic neurological disease, chronic respiratory disease, chronic kidney disease, chronic liver disease, asthma (requiring meds), immunodeficiency, diabetes, BMI ≥40, cancer, other comorbidity, unknown comorbidity, community health office, residential care facility and route of transmission.
$Where an underlying clinical condition was indicated but none of the conditions listed (and pregnancy) were reported. Odds ratios (OR), 95% confidence intervals (95%CI). P-value for overall association (Wald χ2) *p<0.05; ** p<0.001; *** p<0.0001.