TABLE 2.
In Vivo Binding Parameters of 18F-SynVesT-1 and Minimum Scan Time for Stable Measurement, Derived with 1TC Model
| Region | VT (mL/cm3) (baseline, n = 8) | BPND (baseline, n = 8) | Minimum scan time (min) |
| Putamen | 19.3 (14%) | 4.5 (11%) | 30 |
| Insular cortex | 18.8 (16%) | 4.3 (13%) | 30 |
| Temporal cortex | 18.6 (15%) | 4.3 (13%) | 30 |
| Parietal cortex | 17.7 (16%) | 4.0 (15%) | 30 |
| Amygdala | 17.6 (11%) | 4.0 (12%) | 30 |
| Occipital cortex | 17.4 (18%) | 3.9 (17%) | 30 |
| Anterior cingulate cortex | 17.2 (15%) | 3.9 (13%) | 40 |
| Frontal cortex | 16.9 (15%) | 3.8 (12%) | 30 |
| Caudate nucleus | 15.3 (15%) | 3.3 (12%) | 30 |
| Posterior cingulate cortex | 14.2 (27%) | 3.0 (29%) | 30 |
| Thalamus | 13.5 (12%) | 2.8 (12%) | 30 |
| Cerebellum | 13.0 (12%) | 2.7 (15%) | 60 |
| Hippocampus | 13.0 (11%) | 2.7 (14%) | 60 |
| Globus pallidus | 12.6 (20%) | 2.5 (19%) | 30 |
| CS | 3.5 (11%) | 30 |