TABLE 1.
Estimated 18F-LW223 Radiation Dose for Humans Is Within Acceptable Limits for Future Clinical Use
| Estimated absorbed dose (×10−2 mGy/MBq) |
||
| Target organ | Male (n = 8) | Female (n = 5) |
| Adrenals | 2.22 | 3.67 |
| Brain | 0.59 | 0.56 |
| Breasts | 0.72 | 0.86 |
| Gallbladder wall | 2.01 | 2.46 |
| Lower large intestine wall | 7.82 | 9.26 |
| Small intestine | 1.11 | 1.30 |
| Stomach wall | 0.94 | 1.15 |
| Upper large intestine wall | 1.00 | 1.24 |
| Heart wall | 2.03 | 1.89 |
| Kidneys | 1.57 | 1.54 |
| Liver | 1.30 | 1.95 |
| Lung | 3.10 | 3.31 |
| Muscle | 0.80 | 0.98 |
| Ovaries | — | 1.66 |
| Pancreas | 1.03 | 1.26 |
| Red marrow | 0.82 | 0.98 |
| Osteogenic cells | 1.20 | 1.52 |
| Skin | 0.61 | 0.74 |
| Spleen | 0.91 | 1.11 |
| Testes | 0.77 | — |
| Thymus | 0.90 | 1.07 |
| Thyroid | 0.79 | 0.89 |
| Urinary bladder wall | 1.16 | 1.48 |
| Uterus | — | 1.29 |
| Total body | 0.89 | 1.07 |
| Effective dose (mSv/MBq) | 0.02 | 0.02 |