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. 2021 Apr;62(4):446–454. doi: 10.2967/jnumed.120.256180

TABLE 1.

Indications for Treatment to Reduce Osteoporosis or Osteopenia in Postmenopausal Women and Men Aged ≥50 Years with Elevated Fracture Risk

Indication Description
Hip or vertebral fracture Clinically apparent hip or vertebral fracture
Vertebral fracture Vertebral fracture detected on imaging
T‐score
 ≤−2.5 T‐score of ≤ −2.5 at femoral neck, total hip, or lumbar spine
 −1 to −2.5 T‐score of −1 to −2.5 and 10-y probability of ≥3% for hip fracture or of ≥20% for major osteoporotic fracture* estimated with FRAX
*

Hip, clinical spine, humerus, or wrist.