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. 2021 Apr 15;9(4):e3379. doi: 10.1097/GOX.0000000000003379

Table 1.

American Society of Plastic Surgeons Evidence Rating Scale for Therapeutic Studies

Level of Evidence Qualifying Studies
I High-quality, multi-centered or single-centered, randomized controlled trial with adequate power; or systematic review of these studies
II Lesser quality, randomized controlled trial; prospective cohort or comparative study; or systematic review of these studies
III Retrospective cohort or comparative study; case-control study; or systematic review of these studies
IV Case series with pre/post test; or only post test
V Expert opinion developed via consensus process; case report or clinical example; or evidence based on physiology, bench research or “first principles”