Table 1.
Demographic and Clinical Characteristics of Study Cohorts (n = 120)
| Cohort 1 (n = 64) | Cohort 2 (n = 41) | Cohort 3 (n = 15) | Total (n = 120) | P, overall | |
|---|---|---|---|---|---|
| Cohort description | A | B | C | ||
| Patient characteristics, No. (%) | |||||
| Sex | .049 | ||||
| Men | 47 (73.4%) | 21 (51.2%) | 8 (53.3%) | 76 (64.4%) | |
| Women | 17 (26.6%) | 20 (48.8%) | 7 (46.7%) | 44 (36.7%) | |
| Marital status | .715 | ||||
| Married/Living with partner | 51 (79.7%) | 30 (73.2%) | 12 (80.0%) | 93 (77.5%) | |
| Single/Divorced/Living alone | 13 (20.3%) | 11 (26.8%) | 3 (20.0%) | 27 (22.5%) | |
| KPS score | |||||
| KPS < 80 | 12 (18.8%) | 12 (29.3%) | 5 (33.3%) | 29 (24.4%) | |
| KPS ≥ 80 | 52 (81.3%) | 29 (70.7%) | 10 (66.7%) | 90 (75.6%) | |
| Diagnosis | .516 | ||||
| Astrocytoma | 1 (1.6%) | 4 (9.8%) | 2 (13.3%) | 13 (10.8%) | |
| GBM | 50 (78.1%) | 31 (75.6%) | 10 (66.7%) | 91 (75.8%) | |
| Oligodendroglia | 6 (9.4%) | 3 (7.3%) | 3 (20.0%) | 12 (10.0%) | |
| Unknown | 1 (1.6%) | 3 (7.3%) | 0 (0.0%) | 4 (3.3%) | |
| Operation type | .900 | ||||
| Biopsy | 2 (3.1%) | 1 (2.4%) | 0 (0.0%) | 3 (2.5%) | |
| Craniotomy | 49 (76.6%) | 29 (70.7%) | 13 (86.7%) | 91 (75.8%) | |
| Craniotomy + stereo biopsy | 1 (1.6%) | 0 (0.0%) | 0 (0.0%) | 1 (0.8%) | |
| Stereo biopsy | 10 (15.6%) | 10 (24.4%) | 2 (13.3%) | 22 (18.3%) | |
| Unknown | 2 (3.1%) | 1 (2.4%) | 0 (0.0%) | 3 (2.5%) | |
| Localization | .332 | ||||
| Bilateral | 2 (3.1%) | 0 (0.0%) | 1 (6.7%) | 3 (2.5%) | |
| Left hemisphere | 29 (45.3%) | 16 (39.0%) | 6 40.0%) | 51 (42.5%) | |
| Right hemisphere | 31 (48.4%) | 19 (46.4%) | 7 (46.7%) | 57 (47.5%) | |
| Unknown | 2 (3.1%) | 6 (14.6%) | 1 (6.7%) | 9 (7.5%) | |
| Lobe | .801 | ||||
| Frontal | 24 (37.5%) | 16 (39.0%) | 5 (33.3%) | 45 (37.5%) | |
| Occipital | 7 (10.9%) | 6 (14.6%) | 3 (20.0%) | 16 (13.3%) | |
| Parietal | 12 (18.8%) | 3 (7.3%) | 2 (13.3%) | 17 (14.2%) | |
| Temporal | 14 (21.9%) | 9 (22.0%) | 4 (26.7%) | 27 (22.5%) | |
| Unknown | 7 (10.9%) | 7 (17.1%) | 1 (6.7%) | 15 (12.5%) | |
| Current treatment | .000 | ||||
| XRT + chemotherapy | 7 (10.9%) | 29 (70.7%) | 5 (33.3%) | 41 (34.2%) | |
| Chemotherapy only | 1 (1.6%) | 0 (0.0%) | 4 (26.7%) | 5 (4.2%) | |
| XRT only | 2 (3.1%) | 6 (14.6%) | 0 (0.0%) | 8 (6.7%) | |
| Surgery only | 43 (67.2%) | 0 (0.0%) | 4 (26.7%) | 47 (39.2%) | |
| Unknown | 11 (17.2%) | 6 (14.6%) | 2 (13.3%) | 19 (15.8%) |
Abbreviations: GBM, glioblastoma; XRT, external radiation therapy.