Table 2.

Descriptive Statistics for the MDASI-BT Module Test

MDASI-BT module	Mean	SD	Range	LCL	UCL	% = 0a	% 1-4b	% ≥5c	% ≥7d	% Missinge
Core symptoms (rank order)
Fatigue	4.92	2.90	10	4.56	5.28	8.6	30.5	60.9	39.0	0.0
Distress	4.21	2.98	10	3.84	4.58	14.3	35.2	49.6	26.9	0.01
Drowsiness	4.01	3.18	10	3.62	4.41	14.3	43.8	41.9	25.7	0.0
Sadness	3.55	3.17	10	3.16	3.94	23.8	35.2	39.0	27.6	0.02
Sleep disturbance	3.48	3.64	10	3.05	3.91	33.3	30.5	35.3	26.7	0.01
Problem with remembering things	3.40	2.80	9	3.05	3.75	21.9	44.8	33.4	21.0	0.0
Dry mouth	3.03	3.11	10	2.65	3.42	36.2	29.5	32.3	17.1	0.02
Pain	2.98	3.09	10	2.59	3.36	32.4	34.3	33.3	19.0	0.0
Lack of appetite	1.90	2.87	10	1.54	2.25	54.3	25.7	20.0	14.3	0.0
Numbness or tingling	1.70	2.52	10	1.39	2.01	54.3	29.5	16.2	7.6	0.0
Nausea	1.66	3.10	10	1.27	2.04	62.9	19.0	18.1	12.4	0.0
Shortness of breath	1.30	2.22	10	1.02	1.57	62.9	27.6	9.5	3.8	0.0
Vomiting	1.09	2.70	10	0.76	1.43	78.1	6.7	14.3	9.5	0.01
Module items (rank order)
Difficulty concentrating	3.10	2.81	10	2.75	3.45	24.8	47.6	25.7	13.3	0.02
Irritability	2.91	2.71	10	2.57	3.24	26.7	47.6	23.8	14.3	0.02
Difficulty speaking	2.59	2.94	10	2.22	2.95	40.0	38.1	21.0	16.3	0.01
Appearance	2.38	2.91	10	2.02	2.74	36.2	38.1	22.8	13.3	0.03
Weakness	2.29	3.24	10	1.89	2.69	52.4	20.0	27.6	19.0	0.0
Difficulty understanding	2.15	2.54	10	1.83	2.46	41.0	41.9	15.3	8.6	0.02
Vision	2.18	2.94	10	1.82	2.55	48.6	27.6	21.0	12.4	0.03
Change in bowel pattern	2.09	2.70	9	1.76	2.43	48.6	27.6	22.8	13.3	0.01
Seizures	0.40	1.57	8	0.21	0.60	89.5	2.9	4.8	3.8	0.03
Interference items (rank order)
Work, including housework	4.77	3.76	10	4.30	5.24	21.0	25.7	53.3	43.8	0.0
General activity	4.75	3.25	10	4.34	5.15	14.3	32.4	52.3	37.1	0.01
Mood	3.53	2.66	10	3.20	3.86	13.3	46.7	37.1	18.1	0.03
Relations with other people	2.71	2.95	10	2.35	3.08	33.3	36.2	28.5	19.0	0.02
Walking	2.66	3.32	10	2.24	3.07	43.3	28.8	27.6	19.0	0.01
Enjoyment of life	2.36	2.69	10	2.02	2.69	33.3	41.9	22.9	12.4	0.02
Subscale scores
Affective	3.89	2.33	9	3.47	4.31
Cognitive	2.75	2.34	10	2.32	3.17
Focal neurologic deficit	1.99	1.47	5.75	1.72	2.26
Treatment-related	3.10	2.42	10	2.66	3.54
Generalized/disease status	2.00	1.67	7	1.70	2.31
Gastrointestinal	1.47	2.79	10	0.97	1.98
Core items	2.95	1.84	7.77	2.61	3.28
Module items	2.24	1.56	7	1.96	2.52
All symptom items	2.68	1.57	7.29	2.39	2.96
Mean interference (6 items)	3.64	2.47	10	3.37	3.92
Mean WAW (walk-activity-work)	4.24	3.12	10	3.89	4.59
Mean REM (relate-enjoy-mood)	3.04	2.47	10	2.76	3.31

Abbreviations: LCL, lower 95% CL; MDASI-BT, The MD Anderson Symptom Inventory Brain Tumor Module; REM-role functioning, relations with others, enjoyment of life, and mood; UCL, upper 95% CL; WAW, walking, general activity, and work.

MDASI-BT Constructs/Subscales: Affective (distress, fatigue, disturbed sleep, sadness, irritability); Cognitive (difficulty understanding, problem with remembering things, difficulty speaking, difficulty concentrating); Focal neurologic deficit (seizures, numbness or tingling, pain, weakness). Treatment-related (dry mouth, drowsiness, lack of appetite); generalized/disease status (change in appearance, change in vision, change in bowel patterns, shortness of breath); gastrointestinal (nausea, vomiting).

^aPercentage of patients scoring at the floor (score = 0 on the 0-10 scale).

^bPercentage mild.

^cPercentage moderate to severe.

^dPercentage severe.

^ePercentage of missing data.