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The anti-depressant-like effects of RES003 in mice. Mice were treated with vehicle, RES003, and fluoxetine 30 min before being subjected to the (A) SPT and (B) FST. (C) Mice were treated with various doses of RES003 30 min before the locomotor activity test. Results are expressed as mean ± SEM (n = 9–10). ##p < 0.05 and ###p < 0.001 versus vehicle-treated control group. *p < 0.05 and **p < 0.01 versus model group. K: control; M : CUS model; Flu: fluoxetine.
