Table 2.

Studies detailing health risks associated with blood glucose in hypoglycemic range in individuals without diabetes.

S.No	Studies	Type of study	Glycemic variations and outcomes
			Type of glycemic variation	Decision range	Outcomes
1.	Mcgrade et al. (2019) [26]	Retrospective	Blood glucose levels during hospital admissions	Blood glucose <55 mg/dL	Increased in-hospital mortality in patients with blood glucose levels <55 mg/dL.
2.	Tsujimotto et al. (2015) [37]	Retrospective	Hypoglycemia during hospital emergency room visits	Blood glucose <40 mg/dL	Increased mortality risk is associated with blood glucose <40 mg/dL
3.	Egi et al. (2010) [39]	Retrospective	Blood glucose level in critically ill patients	Blood glucose <81 mg/dL	Increased mortality in critically ill patients with blood glucose <81 mg/dL
4.	Preiser et al. (2009) (GLUCONTROL study) [40]	Prospective	Blood glucose	Target blood glucose in intensive insulin therapy (IIT) arm: 80–110 mg/dL	No significant reduction in mortality in IIT arm vs. conventional insulin therapy arm. Trial halted prematurely because of an increased incidence of hypoglycemia in the intensive insulin therapy arm
5.	Mendoza et al. (2005) [38]	Retrospective	Blood glucose levels during hospital admissions	Blood glucose≤50 mg/dL	Increased mortality risk in patients with hypoglycemia