Table 1.
Enriched GO terms found upregulated in D14 embryos as a result of vitrification
| GO ID | G0 term | Source | P value | Fold enrichment |
|---|---|---|---|---|
| G0:0006974 | Cellular response to DNA damage stimulus | Embryo | 3.31E-04 | 3.093 |
| TE | 3.81E-06 | 2.072 | ||
| G0:0006281 | DNA repair | Embryo | 9.17E-04 | 2.939 |
| TE | 2.83E-07 | 2.211 | ||
| G0:0006284 | Base-excision repair | Embryo | 3.68E-02 | 3.918 |
| TE | 9.10E-03 | 2.304 | ||
| G0:0006457 | Protein folding | Embryo | 5.70E-03 | 2.637 |
| TE | 1.27E-05 | 2.046 | ||
| G0:0090002 | Establishment of protein localisation to plasma membrane | Embryo | 1.53E-02 | 4.030 |
| TE | 1.19E-02 | 2.437 | ||
| GO:0090004 | Positive regulation of establishment of protein localisation to plasma membrane | Embryo | 2.29E-02 | 4.521 |
| TE | 8.72E-03 | 2.437 | ||
| G0:0031648 | Protein destabilisation | Embryo | 3.68E-02 | 3.918 |
| TE | 1.94E-04 | 2.880 | ||
| G0:0008283 | Cell proliferation | Embryo | 2.06E-02 | 2.108 |
| G0:0007049 | Cell cycle | Embryo | 1.82E-02 | 2.501 |
| G0:2000648 | Positive regulation of stem cell proliferation | Embryo | 4.25E-02 | 8.816 |
| G0:0030388 | fructose 1,6-bisphosphate metabolic process | Embryo | 3.28E-02 | 10.076 |
| G0:0006468 | Protein phosphorylation | Embryo | 3.16E-02 | 2.059 |
| G0:0008637 | Apoptotic mitochondrial changes | Embryo | 1.95E-02 | 6.717 |
| G0:0000278 | Mitotic cell cycle | TE | 1.51E-02 | 2.400 |
| G0:0006270 | DNA replication initiation | TE | 1.33E-03 | 3.017 |
| G0:0071897 | DNA biosynthetic process | TE | 2.57E-04 | 3.840 |
| G0:0061014 | Positive regulation of mRNA catabolic process | TE | 3.51E-02 | 3.600 |
| G0:0006099 | Tricarboxylic acid cycle | TE | 2.58E-05 | 3.323 |
GO, gene ontology; TE, trophectoderm