Table 2.
Additional upregulated pathways identified by KEGG in D14 embryos as a result of vitrification
| KEGG ID | KEGG term | Source | P value | Fold enrichment |
|---|---|---|---|---|
| bta04110 | Cell cycle | Embryo | 1.32E-03 | 2.974 |
| TE | 7.07E-10 | 2.506 | ||
| bta03410 | Base-excision repair | Embryo | 5.27E-03 | 5.200 |
| TE | 1.97E-07 | 3.757 | ||
| bta01200 | Carbon metabolism | Embryo | 1.39E-03 | 3.148 |
| TE | 9.31E-07 | 2.275 | ||
| bta00051 | Fructose and mannose metabolism | Embryo | 2.16E-02 | 4.613 |
| TE | 1.40E-02 | 2.315 | ||
| bta01230 | Biosynthesis of amino acids | Embryo | 3.10E-03 | 3.625 |
| TE | 8.13E-06 | 2.482 | ||
| bta04115 | p53 signalling pathway | Embryo | 3.66E-02 | 2.820 |
| bta05230 | Central carbon metabolism in cancer | Embryo | 1.29E-03 | 4.151 |
| bta00520 | Amino sugar and nucleotide sugar metabolism | Embryo | 6.06E-03 | 4.171 |
| bta04141 | Protein processing in endoplasmic reticulum | Embryo | 2.53E-04 | 2.877 |
| bta03008 | Ribosome biogenesis in eukaryotes | Embryo | 1.21E-08 | 2.808 |
| bta03030 | DNA replication | TE | 1.26E-04 | 2.900 |
| bta03015 | Messenger RNA surveillance pathway | TE | 1.20E-06 | 2.420 |
| bta03018 | RNA degradation | TE | 7.01E-04 | 2.061 |
| bta00020 | Citrate cycle (TCA) | TE | 8.69E-06 | 3.480 |
| bta00240 | Pyrimidine metabolism | TE | 4.38E-06 | 2.264 |
| bta00970 | Aminoacyl-tRNA biosynthesis | TE | 2.90E-06 | 3.045 |
TE, trophectoderm