Table 1.
No NAFLD (n = 20) | NAFLD (n = 32) | p valueb | |
---|---|---|---|
Age (years) | 42.13 ± 8.7 | 45.22 ± 10.9 | 0.35 |
Gender (F%) | 87% | 65% | 0.03a |
BMI (Kg/m2) | 43.8 ± 6.1 | 42.1 ± 5.4 | 0.37 |
Waist circumference (cm) | 128.1 ± 12.5 | 127.7 ± 16.1 | 0.94 |
PAS (mmHg) | 129.2 ± 10.3 | 126.9 ± 11.8 | 0.47 |
PAD (mmHg) | 84.2 ± 6.9 | 84.9 ± 17.4 | 0.86 |
AST (IU/l) | 20.8 ± 7.8 | 29 ± 13.7 | 0.032 |
ALT (IU/l) | 21.9 ± 10.4 | 41 ± 23.2 | < 0.001 |
GGT (UI/l) | 20.16 ± 7.2 | 30.8 ± 17.7 | 0.009 |
Total cholesterol (mg/dl) | 204.7 ± 30.6 | 190.6 ± 29.6 | 0.15 |
HDL-C (mg/dl) | 48.8 ± 11.3 | 45.4 ± 10.7 | 0.34 |
LDL-C (mg/dl) | 131.6 ± 23.1 | 113.6 ± 26.6 | 0.03 |
Triglycerides (mg/dl) | 109 ± 39 | 167.1 ± 74.5 | 0.006 |
Total bilirubin (mg/dl) | 3.9 ± 6.7 | 2.25 ± 3.9 | 0.34 |
Direct bilirubin (mg/dl) | 1.40 ± 2.84 | 0.92 ± 1.9 | 0.58 |
FBG (mg/dl) | 96.8 ± 12.9 | 103.8 ± 23 | 0.23 |
HbA1c (%) | 5.3 ± 0.3 | 5.7 ± 0.63 | 0.05 |
FBI (IU/mL) | 11.9 ± 7 | 15.3 ± 8.2 | 0.29 |
HOMA-IR | 2.85 ± 1.5 | 3.82 ± 2.4 | 0.24 |
HOMA-β% | 149.6 ± 145.7 | 169.2 ± 70.5 | 0.69 |
FIB-4 | 0.8 ± 0.25 | 1.04 ± 0.3 | 0.039 |
Steatosis % [median(range)] | 3.5 (0.75–5) | 60 (30–70) | < 0.001 |
Steatosis grade (n, 0/1/2/3) | 20/0/0/0 | 0/8/8/16 | < 0.001 |
Lobular inflammation (n, 0/1/2) | 8/12/0 | 14/8/10 | 0.10 |
Ballooning (n, 0/1/2) | 19/1/0 | 12/15/5 | < 0.001 |
Fibrosis (F0/F1/F2/F3/F4) | 10/10/0/0/0 | 10/18/3/1/0 | 0.20 |
T test applied
a test applied
bMann–Whitney test applied. Statistical significance is related to the comparison between NAFLD and non-NAFLD sub-groups