Table 2:
Demographic characteristics and case status by cohort and cluster assignment by ROPA.
| OPPERA, n (%) | n=4278 | A (n=1426) |
PS (n=2062) |
GS (n=790) |
P† |
|---|---|---|---|---|---|
| Male | 1637 | 839 (0.51) | 558 (0.34) | 240 (0.15) | <0.0001 |
| Female | 2641 | 587 (0.22) | 1504 (0.57) | 550 (0.21) | |
| Non-Hispanic white | 2361 | 780 (0.33) | 1126 (0.48) | 455 (0.19) | 0.08 |
| African American | 1171 | 381 (0.33) | 596 (0.51) | 194 (0.17) | |
| Asian | 340 | 111 (0.33) | 160 (0.47) | 69 (0.2) | |
| Hispanic | 273 | 102 (0.37) | 129 (0.47) | 42 (0.15) | |
| Other | 133 | 52 (0.39) | 51 (0.38) | 30 (0.23) | |
| Age <18 | 0 | 0 (0) | 0 (0) | 0 (0) | <0.0001 |
| Age 18-24 | 2067 | 730 (0.35) | 1027 (0.5) | 310 (0.15) | |
| Age 25-34 | 1228 | 379 (0.31) | 593 (0.48) | 256 (0.21) | |
| Age 35-44 | 983 | 317 (0.32) | 442 (0.45) | 224 (0.23) | |
| Age >44 | 0 | 0 (0) | 0 (0) | 0 (0) | |
| Cases | 1031 | 88 (0.09) | 540 (0.52) | 403 (0.39) | <0.0001 |
| Controls | 3247 | 1338 (0.41) | 1522 (0.47) | 387 (0.12) | |
| DIPT, n (%) | n=641 | A (n=230) | PS (n=259) | GS (n=152) |
P† |
| Male | 190 | 100 (0.53) | 49 (0.26) | 41 (0.22) | <0.0001 |
| Female | 451 | 130 (0.29) | 210 (0.47) | 111 (0.25) | |
| White | 518 | 177 (0.34) | 215 (0.42) | 126 (0.24) | 0.06 |
| African American | 64 | 20 (0.31) | 29 (0.45) | 15 (0.23) | |
| Asian | 20 | 12 (0.6) | 5 (0.25) | 3 (0.15) | |
| Other | 39 | 21 (0.54) | 10 (0.26) | 8 (0.21) | |
| Age <18 | 2 | 1 (0.5) | 0 (0) | 1 (0.5) | 0.37 |
| Age 18-24 | 30 | 6 (0.2) | 13 (0.43) | 11 (0.37) | |
| Age 25-34 | 88 | 36 (0.41) | 33 (0.38) | 19 (0.22) | |
| Age 35-44 | 120 | 49 (0.41) | 47 (0.39) | 24 (0.2) | |
| Age >44 | 401 | 138 (0.34) | 166 (0.41) | 97 (0.24) | |
| CPPC, n (%) | n=666 | A (n=388) | PS (n=127) | GS (n=151) |
P† |
| Male | 81 | 67 (0.83) | 6 (0.07) | 8 (0.1) | <0.0001 |
| Female | 585 | 321 (0.55) | 121 (0.21) | 143 (0.24) | |
| White | 466 | 274 (0.59) | 89 (0.19) | 103 (0.22) | 0.47 |
| African American | 148 | 82 (0.55) | 25 (0.17) | 41 (0.28) | |
| Asian | 18 | 12 (0.67) | 4 (0.22) | 2 (0.11) | |
| Other | 34 | 20 (0.59) | 9 (0.26) | 5 (0.15) | |
| Age <18 | 0 | 0 (0) | 0 (0) | 0 (0) | 0.0002 |
| Age 18-24 | 113 | 74 (0.65) | 27 (0.24) | 12 (0.11) | |
| Age 25-34 | 231 | 132 (0.57) | 52 (0.23) | 47 (0.2) | |
| Age 35-44 | 168 | 84 (0.5) | 31 (0.18) | 53 (0.32) | |
| Age >44 | 154 | 98 (0.64) | 17 (0.11) | 39 (0.25) | |
| Healthy control | 240 | 211 (0.88) | 17 (0.07) | 12 (0.05) | |
| Fibromyalgia | 104 | 5 (0.05) | 32 (0.31) | 67 (0.64) | |
| Episodic migraine | 273 | 96 (0.35) | 74 (0.27) | 103 (0.38) | |
| Irritable bowel syndrome | 228 | 82 (0.36) | 56 (0.25) | 90 (0.39) | |
| Temporomandibular disorder | 176 | 32 (0.18) | 54 (0.31) | 90 (0.51) | |
| Vulvar vestibulitis (n=585) | 146 | 53 (0.36) | 39 (0.27) | 54 (0.37) |
*
Indicates that the sample is only among female patients, where n=585.
†
Indicates that the p-value tests the null hypothesis that the percentage in each cluster does not differ across levels of the demographic feature.