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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Nat Protoc. 2021 Mar 10;16(4):2088–2108. doi: 10.1038/s41596-020-00485-y

Figure 1.

Figure 1.

Recording lineages using synthetically induced somatic mutations in the genome. (a) A number of loci (n) accumulate heritable mutations as cells divide, thereby recording the lineage relationship of the cells in an array of mutational barcodes across an embryo. Gray domino, active barcoding elements; colored dominos, fixed mutant barcoding elements. (b) A cell division tree with the number of terminal branches (k) and levels shown.