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. Author manuscript; available in PMC: 2022 Apr 16.
Published in final edited form as: Circ Res. 2021 Feb 17:10.1161/CIRCRESAHA.120.318170. doi: 10.1161/CIRCRESAHA.120.318170

Figure 1: CASK expression is regulated in hypertrophy and HF.

Figure 1:

A) Western blots (left panels) and mean analysis (right panel) of CASK expression in human left ventricular (LV) myocardium from patients with end-stage heart failure (HF) or patients with aortic stenosis (AS) in comparison to LV samples from healthy organ donor hearts (NF). CASK expression is increased in AS compared to HF and NF. Data are normally distributed (Shapiro-Wilk-test). *One way ANOVA p=0.0017, Holm-Sidak post-test (p in figure, n=mice). B) Original blots analyzing CASK (upper panel) and CaMKII (lower panel) expression in immunoprecipitated proteins CASK (anti-CASK), NaV1.5 (anti-NaV1.5) and CaMKII (anti-CaMKII) from homogenates of HF vs. NF.