Figure 1.

Terpenes Induce Cannabimimetic Tetrad Behaviors in Mice. Behavioral analysis data from Figs. S1-S3 represented in a radar chart format. The percent change from baseline for each terpene in each behavior was determined; the peak effect for tail flick was selected (Fig. S1) while the other behaviors only had a single time point. This percent change was then normalized to the % change of 5.6 mg/kg WIN55,212-2 (1.0 on the chart above). The chart demonstrates that while all terpenes induce all 4 tetrad behaviors, they do so with varying efficacy; they also vary whether the effect is stronger or weaker than the positive control WIN55,212-2.