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a Tissue scores for senescence-associated β-galactosidase (SAβ-gal) staining in SQAT significantly and positively associated with chronological age (r = 0.31, p < 0.05). b Circulating plasminogen activator inhibitor 1 (PAI-1), a proposed biomarker of senescence, was significantly and positively associate with chronological age (r = 0.39, p = 0.01)
