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. 2020 Oct 9;43(1):239–252. doi: 10.1007/s11357-020-00276-z

Table 4.

Associations of low- and high-intensity physical activity time and high sedentary time with node degree of the frontal, temporal, parietal, and occipital lobe

Degree Degree Degree Degree
Frontal lobe Temporal lobe Parietal lobe Occipital lobe
stβ (95% CI) P stβ (95% CI) P stβ (95% CI) P stβ (95% CI) P
LPA time (high to low)
Model 1 − 0.020 (− 0.067, 0.027) 0.420 − 0.031 (− 0.079, 0.017) 0.208 0.041 (− 0.007, 0.089) 0.097 0.016 (− 0.032, 0.065) 0.501
Model 2 − 0.001 (− 0.048, 0.047) 0.984 − 0.028 (− 0.077, 0.021) 0.266 0.034 (− 0.014, 0.083) 0.172 0.021 (− 0.028, 0.070) 0.397
Model 3 0.007 (− 0.042, 0.055) 0.786 − 0.027 (− 0.077, 0.024) 0.301 0.029 (− 0.021, 0.079) 0.262 0.019 (− 0.031, 0.069) 0.459
HPA time (high to low)
Model 1 − 0.076 (− 0.124, − 0.028) 0.002 − 0.068 (− 0.118, − 0.019) 0.007 − 0.005 (− 0.055, 0.044) 0.835 − 0.001 (− 0.051, 0.048) 0.956
Model 2 − 0.058 (− 0.106, − 0.009) 0.020 − 0.067 (− 0.117, − 0.016) 0.010 − 0.014 (− 0.064, 0.036) 0.584 0.003 (− 0.047, 0.053) 0.909
Model 3 − 0.054 (− 0.104, − 0.003) 0.038 − 0.066 (− 0.118, − 0.014) 0.014 − 0.025 (− 0.077, 0.027) 0.347 − 0.002 (− 0.054, 0.051) 0.954
Sedentary time (low to high)
Model 1 − 0.039 (− 0.089, 0.011) 0.126 − 0.032 (− 0.083, 0.020) 0.226 0.032 (− 0.019, 0.083) 0.227 0.004 (− 0.048, 0.055) 0.891
Model 2 − 0.017 (− 0.068, 0.034) 0.519 − 0.028 (− 0.082, 0.026) 0.296 0.024 (− 0.029, 0.071) 0.385 0.009 (− 0.044, 0.061) 0.745
Model 3 − 0.010 (− 0.062, 0.043) 0.721 − 0.028 (− 0.082, 0.026) 0.312 0.017 (− 0.036, 0.071) 0.535 0.003 (− 0.051, 0.058) 0.898

Associations of physical activity measures (minutes/day) with node degree. Regression coefficients and 95% CI indicate the mean difference in node degree per SD higher PA or lower sedentary time. Model 1, adjusted for age, sex, education level, MRI lag time, and wake time. Model 2, additionally adjusted for diabetes status. Model 3, additionally adjusted for BMI, systolic blood pressure, antihypertensive medication, total-to-HDL-cholesterol ratio, lipid-modifying medication, smoking status, alcohol use, and history of cardiovascular disease

Italic values indicate p<0.05