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. 2021 Apr 15;11:8253. doi: 10.1038/s41598-021-87683-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Characterization of blastocyst- and liver-specific H3K4me3 modifications. (a) Processing of ChIP-peaks in liver and blastocyst samples. The numbers show those of the peaks. The sum of common (intersect) and specific peak numbers is not equal to the original peak number in each sample because some peaks were separated into multiple peaks to represent intersects. (b) Top 10 significant GO terms for biological process enriched by the genes with the top 100 highest peak occupancy rates. Gene n. represents the numbers of related genes. FDR(B) indicates the Benjamin false discovery rate. (c) Examples of the H3K4me3 landscape of liver- (ARG1) and blastocyst-specific (GATA2) peaks around their TSSs. Five-kb graduations are shown in the top scale.