Table 2. Summary of HIFU treatment in patients with HCC and cirrhosis.

Study	Treatment	Year	No. of patients	Cirrhosis	Tumor size	Complete response	Survival	Complication rate
Xu et al. (82)	HIFU	2011	145	44% Child B or above	<2, 2–5, >5 cm	–	80% (2 years), 51.4%, 46.5%	2.1% (major complications)
Cheung et al. (97)	HIFU	2012	47	34% Child B or above	<3 cm	90%	79.8% (3 years)	6.3% (major complications)
Wu et al. (90)	HIFU	2004	55	Child A and B	>8 cm	3.6% (90% partial response)	35.3% (18 months)	23.6% (minor complications) no major complication
Li et al. (91)	HIFU	2007	151	51% Child B or above	>5 cm	28.5% (60.3% partial response)	30.9% (2 years)	15% (major complications)
Cheung et al. (92)	HIFU	2014	26	34% Child B or above	>3 cm	50%	49.2% (3 years)	56% (minor complications), no major complication
Wu et al. (93)	HIFU + TACE	2005	24	Mainly Child A	50% >10 cm	64% partial response	42.9% (1 year)	25% (minor complications) no major complication
Li et al. (94)	HIFU + TACE	2010	44	22.7% Child B or above	Mainly >5 cm	27.3% (45.5% partial response)	50% (1 year)	29.6% (minor complications), no major complication