Table 1. Analysis of the correlation between mutated genes and clinical characteristics.
Characteristic | TP53 | TERT | TP53 + TERT | CTNNB1 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
WT | Mutant | P value | WT | Mutant | P value | WT | Mutant | P value | WT | Mutant | P value | ||||
Gender (male/female) | 65/8 | 84/11 | 0.900 | 84/8 | 65/11 | 0.239 | 102/12 | 47/7 | 0.641 | 114/16 | 35/3 | 0.450 | |||
Age (<55/≥55) | 30/43 | 47/48 | 0.280 | 41/51 | 36/40 | 0.717 | 52/62 | 25/29 | 0.934 | 61/69 | 16/22 | 0.600 | |||
*Liver fibrosis (123/4) | 34/35 | 35/56 | 0.171 | 39/50 | 30/41 | 0.842 | 48/61 | 21/30 | 0.734 | 51/73 | 18/18 | 0.344 | |||
*Differentiation (12/34) | 43/27 | 31/62 | 0.000 | 43/47 | 31/42 | 0.498 | 57/53 | 17/36 | 0.018 | 51/75 | 23/14 | 0.020 | |||
TNM (12/34) | 52/21 | 65/30 | 0.694 | 66/26 | 51/25 | 0.516 | 82/32 | 35/19 | 0.349 | 90/40 | 27/11 | 0.830 | |||
BCLC (01/23) | 43/30 | 51/44 | 0.499 | 56/36 | 38/38 | 0.158 | 8/46 | 26/28 | 0.161 | 72/58 | 22/16 | 0.784 | |||
AFP (<25/≥25 ng/L) | 31/40 | 37/58 | 0.541 | 39/51 | 29/47 | 0.499 | 49/63 | 19/35 | 0.293 | 45/84 | 23/14 | 0.003 | |||
Hepatitis B (without/with) | 11/62 | 13/82 | 0.799 | 12/80 | 12/64 | 0.613 | 15/99 | 9/45 | 0.544 | 14/116 | 10/28 | 0.016 | |||
Tumor size (≤5/>5 cm) | 41/32 | 55/40 | 0.822 | 56/36 | 40/36 | 0.283 | 69/45 | 27/27 | 0.198 | 76/54 | 20/18 | 0.523 | |||
Tumor number (single/multiple) | 48/25 | 57/38 | 0.445 | 58/34 | 47/29 | 0.873 | 71/43 | 34/20 | 0.932 | 82/48 | 23/15 | 0.775 | |||
Hepatic capsule (without/with) | 38/31 | 42/49 | 0.264 | 55/34 | 25/46 | 0.001 | 64/45 | 16/35 | 0.001 | 60/64 | 20/16 | 0.449 | |||
*Microcarcinoma suppository (without/with) | 43/23 | 29/60 | 0.000 | 44/41 | 28/42 | 0.144 | 57/47 | 15/36 | 0.003 | 58/62 | 14/21 | 0.384 |
*, a small amount of data is missing.