Table 2. Comparison of gene mutational frequencies in different ethnicities.
Gene | Korean (7) (n=231) (%) | Japanese (8) (n=503) (%) | European (9) (n=243) (%) | TCGA (n=366) (%) | Chinese (n=168) (%) |
---|---|---|---|---|---|
TP53 | 32 | 31 | 24 | 33 | 57 |
TERT | 23 | 55 | 60 | 44* | 45 |
CTNNB1 | 23 | 31 | 35 | 27 | 23 |
AXIN1 | 7 | 6 | 11 | 8 | 14 |
RB1 | 8 | 4 | 4 | 11 | 12 |
TSC2 | NA | 5 | 5 | 5 | 11 |
*, The TCGA database was sequenced by WES and TERT promoter mutations were not detected; 196 cases of Sanger sequencing results of TCGA database by David A. Wheeler et al. (10).