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. 2021 Apr 16;76:e2587. doi: 10.6061/clinics/2021/e2587

Table 4. Comparison of the IHC subtypes obtained in the MIUCB and in the respective LNM using CK5 and CK20.

LNM IHC subtype CK5/CK20 n (%)
basal luminal double negative double positive Total
MIUCB IHC subtype CK5/CK20
    basal 16 (21.9) 0 (0.0) 2 (2.7) 4 (5.5) 22 (30.1)
    luminal 0 (0.0) 22 (30.1) 2 (2.7) 5 (6.8) 29 (39.7)
    double negative 0 (0.0) 2 (2.7) 5 (6.8) 1 (1.4) 8 (11.0)
    double positive 1 (1.4) 5 (6.8) 0 (0.0) 8 (11.0) 14 (19.2)
    Total 17 (23.3) 29 (39.7) 9 (12.3) 18 (24.7) 73 (100.0)

McNemar-Bowker test: p value=0.440; Kappa coefficient=0.58.

Abbreviations: IHC, immunohistochemical; MIUCB, muscle-invasive urothelial carcinomas of the bladder; LNM, lymph node metastasis.