Table 5. Comparison of the IHC subtypes obtained in the MIUCB and in the respective LNM using CK5 and GATA3.
LNM IHC subtype CK5/GATA3 n (%) | |||||
---|---|---|---|---|---|
basal | luminal | double negative | double positive | Total | |
MIUCB IHC subtype CK5/GATA3 | |||||
basal | 4 (5.3) | 0 (0.0) | 0 (0.0) | 4 (5.3) | 8 (10.5) |
luminal | 0 (0.0) | 28 (36.8) | 2 (2.6) | 6 (7.9) | 36 (47.4) |
double negative | 0 (0.0) | 1 (1.3) | 2 (2.6) | 0 (0.0) | 3 (3.9) |
double positive | 2 (2.6) | 8 (10.5) | 0 (0.0) | 19 (25.0) | 29 (38.2) |
Total | 6 (7.9) | 37 (48.7) | 4 (5.3) | 29 (38.2) | 76 (100.0) |
McNemar-Bowker test: p value=0.732; Kappa coefficient=0.51.
Abbreviations: IHC, immunohistochemical; MIUCB, muscle-invasive urothelial carcinomas of the bladder; LNM, lymph node metastasis.