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(A) Representative trace chart depicting dose-dependent fargesin inhibition of IORAI1 at 1, 3, 10, 30, 100, and 300 µM. (B) Typical current–voltage (I–V) relationships describing inhibitory proportion of fargesin at a range of concentrations (1–300 µM). (C) Concentration dependence of IORAI1 inhibition by fargesin at −120 mV and fitted dose-response curves. Values are presented as mean ± SEM.
