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. 2021 Mar 10;19:1759–1785. doi: 10.1016/j.csbj.2021.03.003

Table 7.

Characteristics and findings of the studies examining the association between hypertension and type 2 diabetes.

Work Year Study Design Sample size (%DM) %M/W Age (Years) Ethnicity Follow-up duration (Years) Adjusted variables Findings
[166] 1999 RS PCS 7594 (7.9%) 100/0 30–65 Japanese 16 Age, BMI, alcohol consumption, smoking habits, leisure time physical activity, and parental history of diabetes Blood pressure in mmHg
130/85
130–139/85–89
139/89
RR
1.0
1.39 (1.14–1.69)
1.76 (1.43–2.16)
[167] 2000 ARIC [36] PCS 12550 44.39/ 55.61 45–64 Blacks and Whites (USA) 3 and 6 Age, sex, race, BMI, WHR, educational level, smoking status, alcohol consumption, physical activity, systolic and diastolic blood pressure, fasting serum insulin concentration, history of hypercholesterolemia, cardiovuscular diseases, pulmonary dieseases, renal insufficiency, and family history of diabetes Hypertension medication
None
ACE inhibitor
Beta-blocker
Calcium-channel antagonist
Thiazide diuretic
HR
1.0
0.98 (0.72–1.34)
1.28 (1.04–1.57)
1.17 (0.83–1.66)
0.91 (0.73–1.13)
[168] 2007 WHS [185] PCS 38172 (4.38%) 0/100 45 USA 10.2 Age, ethnicity, smoking, BMI, exercise, alcohol consumption, history of hypercholesterolameia, educational level, family history of diabetes, and randomized treatment assignments Blood pressure in mmHg
120–129/75–84
130–139/85–89
140/90
HR
1.0
1.45 (1.23–1.71)
2.03 (1.77–2.32)
[170] 2011 ARIC [36], CARDIA [186], and FHS [187] PCS 10893 (9.45%) 43/57 35–54 African-American and Whites (USA) Median 8.9 Age, sex, BMI, fasting glucose, DL cholesterol and triglycerids Blood pressure in mmHg
leq119/leq79
120–139/80–89
140/90
HR
1.0
1.32 (1.09–1.61)
1.25 (1.03–1.53)
[188] 2012 GPPS [189] PCS 7494 (12.02%) 100/0 47–55 Swedish 35 Age, BMI, cholesterol level, antihypertensive treatment, smoking, physical activity and occupational class Blood pressure in mmHg
leq129
130–159
160
84
85–89
90
HR
1.0
1.43 (1.12–1.84)
1.95 (1.55–2.46)
1.0
1.34 (1.12–1.62)
1.08 (1.06–1.11)
[169] 2015 KGES [190] PCS 7150 (14.7%) 47.46/ 52.54 40–69 Korean 8 Age, BMI, fasting plasma glucose, total cholesterol, HDL cholesterol, family history of diabetes, education, alcohol consumption and smoking status Blood pressure in mmHg
120/80
120–139/80–89 (M)
120–139/80–89 (W)
140/90 (M)
140/90 (W)
HR
1.0
1.24 (1.01–1.52)
1.30 (1.03–1.64)
1.65 (1.34–2.05)
1.34 (1.05–1.70)

RS-Random Sample, ARIC-Atherosclerosis Risk in Communities, WHS, Women’s Health Study, CARDIA-Coronary Artery Risk Development in Young Adults, FHS-Framingham Heart Study, GPPS-Gothenburg Primary Prevention Study, KGES-Korean Genome and Epidemiology Study, M-Men, W-Women, PCS-Prospective Cohort Study.