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. 2021 Mar 7;10:100106. doi: 10.1016/j.mtbio.2021.100106

Table 3.

Conventional mechanical testing methods for the characterization of blood vessel substitutes, main parameters, manipulated variables, and the responding mechanical properties.

Testing method Sample geometry Test direction Deformation rate range Strain/pressure rangea Mechanical properties References
Compression Cylindrical/Ring Longitudinal 0.01–0.2 mm/min YM: 0–30% SB, EB, YM [32,33]
Rectangular Radial [34]
Tensile Rectangular Longitudinal 1–50 mm/min YM: 0–30% SB, EB, YM [35,36]
Circumferential
Dogbone Longitudinal [37,38]
Circumferential
Ring Circumferential SB, EB YM, BP, C [[39], [40], [41], [42], [43], [44], [45]]
Tensile stress-relaxation Ring Longitudinal 1–50 mm/min YM: 10–70% SB, EB IEM, EEM BP, C [46]
Circumferential [41,[46], [47], [48], [49], [50], [51], [52], [53]]
Creep Rectangular Circumferential 1.6 mm/s 30–50% of SB CP [54]
Ring [42,50,55]
Burst pressure Tubular Circumferential 0.1–100 mL/min 0 until rupture BP [35,[37], [38], [39],[42], [43], [44],55,56]
Compliance Tubular Circumferential 4–100 mL/min 50–180 mmHg C [35,38,39,43,49,55,56]
DMA Rectangular Longitudinal 0.1–10 Hz 5–16% E′, E″, tanδ [57]
Ring Circumferential [33,58]

DMA, dynamic mechanical analysis; SB, strength at break; EB, elongation at break; YM, Young elastic modulus; IEM, initial elastic modulus; EEM, equilibrium elastic modulus; CP, creep profile; BP, burst pressure; C, compliance; E′, storage modulus; E′′, loss modulus; tanδ, damping factor.

a

Strain/pressure range used for the calculation of the mechanical properties.