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. 2021 Apr 12;66:103336. doi: 10.1016/j.ebiom.2021.103336

Table 3.

Clinical characteristics of CRS subgroups.

E (n =19) LP (n =104) E+LP (n=31) N+LP (n=4) χ2 P
Age 47 (36,59) 37 (29.25,52.75) 37 (29,48) 44.5 (22.25,64.5) 2.971 0.396
Gender (M/F) 14/5 77/27 23/8 3/1 0.222 1.000
Onset time (months) 60 (24,120) 48 (12,120) 36(12,120) 39 (4.5,288) 1.142 0.767
Itching (Y/N) 8/11 15/89 20/11 0/4 31.306 <0.001*
Sneezing (Y/N) 8/11 17/87 21/10 0/4 31.334 0.013*
Asthma (Y/N) 4/15 4/100 5/26 0/4 9.106 0.016*
Rhinorrhea score 6 (5,7) 6 (5,7) 6 (5,7) 6 (3,6.75) 1.298 0.730
Nasal obstruction score 6 (6,7) 6 (5,6.75) 6 (5,6) 6 (5.25,6.75) 3.578 0.311
Olfactory dysfunction score 6 (5,7) 5 (2.25,6) 6 (3,8) 6 (2.25,6.75) 7.058 0.070
Headache/facial pain score 2 (1,6) 2 (1,4.75) 3 (1,5) 3 (0.25,5) 1.473 0.689
Total VAS score 21 (19,24) 19 (15,21) 21 (15,24) 21.5 (10.75,24.75) 6.397 0.094
Lund-Kennedy score 8 (6,10) 8 (5,10) 6 (4,10) 6.5 (4.5,10.75) 1.737 0.629
Lund-Mackay score 11 (9,16) 11 (8,18) 10 (8,14) 16 (8,19.5) 1.360 0.715
Total IgE (IU/ml) (1^/2#/3&) 5/3/11 59/12/33 5/14/12 4/0/0 15.878 0.001*
Peripheral lym% 31.9 (29.09,34.32) 32.7 (28.45,39.05) 31.72 (27.48,36.92) 31.49 (27.89,32.07) 2.865 0.413
Peripheral neu% 53.17 (49.25,57.06) 54.85 (48.24,59.92) 49.16 (45.56,56.31) 55.29 (51.1,61.55) 5.452 0.142
Peripheral eos% 6.9 (3.5,9.87) 2.9 (1.84,5) 7.48 (5.23,9.66) 4.32 (1.9,6.18) 40.377 <0.001*
Peripheral bas% 0.46 (0.33,0.96) 0.58 (0.34,0.66) 0.71 (0.38,0.96) 0.48 (0.28,1.13) 3.355 0.340
Recurrence$ (Y/N) 12/4 5/66 15/11 1/2 44.459 <0.001*

E= eosinophil-dominant phenotypes; LP: plasma cells and lymphocyte-dominant phenotypes;

E+LP= eosinophils, plasma cells and lymphocyte-dominant phenotypes;

N+LP= neutrophils, plasma cells and lymphocyte-dominant phenotypes;

1^, Total IgE<100 IU/ml; 2#, 100 IU/ml <Total IgE<200 IU/ml; 3&, Total IgE>200 IU/ml.

$data from a retrospective cohort.

*P<0.05.