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. 2021 Mar 16;22(5):275–290. doi: 10.2217/pgs-2020-0143

Table 1. . Pharmacokinetic parameters of various formulations of oxycodone.

Formulations Bioavailability Time to peak concentration Half-life
IV 100% 2–3 h
IM 100% ∼1 h ∼4.9 h
Oral 50–90% 1–1.5 h 3–5 h
Oral (extended release) 60–87% ∼2.6 h ∼8 h
Rectal ∼62% ∼2.8 h ∼3.7 h