Table 1. . Pharmacokinetic parameters of various formulations of oxycodone.
Formulations | Bioavailability | Time to peak concentration | Half-life |
---|---|---|---|
IV | 100% | – | 2–3 h |
IM | 100% | ∼1 h | ∼4.9 h |
Oral | 50–90% | 1–1.5 h | 3–5 h |
Oral (extended release) | 60–87% | ∼2.6 h | ∼8 h |
Rectal | ∼62% | ∼2.8 h | ∼3.7 h |