Table 1.
Clinical and biochemical index of the patients at baseline
| MSC (N = 11) | Rituximab (N = 11) | P value | |
|---|---|---|---|
| Gender (male)(%) | 9 (81.8%) | 10 (90.9%) | 1.000 |
| Age (years) | 48.64 ± 7.94 | 43.64 ± 13.25 | 0.296 |
| WBC (× 109) | 7.32 (3.86–11.60) | 9.29 (6.69–15.66) | 0.365 |
| PLT (×109/L) | 71.00 (47.00–90.00) | 104.00 (75.00–201.00) | 0.056 |
| AST (U/L) | 69.00 (21.00–111.00) | 97.00 (53.00–180.00) | 0.217 |
| ALT (U/L) | 30.00 (9.00–94.00) | 99.00 (18.00–233.00) | 0.171 |
| ALB (g/L) | 32.20 (30.80–35.80) | 34.20 (33.20–36.20) | 0.773 |
| TBIL (umol/L) | 420.73 (38.45–541.73) | 590.07 (202.35–702.68) | 0.116 |
| ALP (U/L) | 99.00 (95.00–124.00) | 99.00 (71.00–116.00) | 0.478 |
| GGT (U/L) | 49.00 (33.00–77.00) | 51.00 (42.00–75.00) | 1.000 |
| PT (s) | 25.60 (20.60–37.60) | 33.20 (29.10–38.80) | 0.251 |
| INR | 2.31 (1.75–3.67) | 3.17 (2.71–3.98) | 0.270 |
| CREAT (umol/L) | 76.00 (45.00–114.00) | 71.00 (56.00–174.00) | 0.748 |
| BUN (mmol/L) | 7.73 (5.01–9.16) | 5.35 (3.18–15.44) | 0.699 |
| IgM | 8.00 (8.00–32.00) | 8.00 (8.00–16.00) | 0.898 |
| IgG | 16.00 (8.00–32.00) | 32.00 (2.00–64.00) | 0.478 |
| CPS score | 11.82 ± 1.66 | 11.46 ± 1.57 | 0.604 |
| MELD score | 31.00 (30.00–40.00) | 40.00 (32.00–40.00) | 0.217 |
| Donor age (years) | 41.09 ± 15.78 | 42.73 ± 8.63 | 0.767 |
| Cold ischemia time(h) | 6.00 (6.00–7.50) | 6.00 (4.72–7.00) | 0.270 |
| Operation time (min) | 443.64 ± 41.65 | 425.64 ± 60.23 | 0.425 |
| Anhepatic phase time (min) | 45.00 (42.00–55.00) | 43.00 (40.00–55.00) | 0.847 |
| Intraoperative blood loss (mL) | 1500.00 (1500.00–2400.00) | 1500.00 (1000.00–2000.00) | 0.365 |
| Blood transfusion volume | |||
| RBC (U) | 12.00 (6.00–16.00) | 9.50 (7.50–16.00) | 0.797 |
| FFP (mL) | 2400.00 (2100.00–3600.00) | 3050.00 (2000.00–4000.00) | 0.606 |
| Cryo (U) | 28.00 ± 15.28 | 36.05 ± 8.08 | 0.138 |
Abbreviations: MSC mesenchymal stem cell, WBC white blood cell, PLT platelet, AST aspartate aminotransferase, ALT alanine aminotransferase, ALB albumin, TBIL total bilirubin, ALP alkaline phosphatase, GGT gamma-glutamyl transferase, PT prothrombin time, INR international normalized ratio, CREAT creatinine, BUN blood urea nitrogen, CPS Child-Pugh score, MELD model for end stage liver disease, RBC red blood cell, FFP fresh frozen plasma, Cryo cryoprecipitate