Table 1.
Summary of major features of the patient’s history, clinical symptoms and laboratory findings, including SARS-CoV-2 testing (reference values given in brackets).
| Day 1 | Day 15 | Day 18 | Day 19 | Day 20 | Day 23 | Day 24 | Day 25 | Day 26 | |
|---|---|---|---|---|---|---|---|---|---|
| Major event | Vaccination | Collapse during breakfast | Admission to hospital; gastroscopy (mild gastritis) | Abdominal ultrasound, initiating intravenous iron application | Colonoscopy (ischemic colitis), initiating mesalazine | Acute renal insufficiency, initiating intravenous glucose application | Patient in same hospital room has positive SARS-CoV-2 RT-PCR test (Ct, 15) | Patient somnolent, initiating antibiotic therapy, chest radiograph with minimal infiltrates | Death at 14:30 |
| Leading clinical symptoms | No relevant symptoms recorded | No further relevant symptoms recorded | Diarrhea | Anemia | Anemia | Lung auscultation with any pathological signs, hypernatremia | Hypernatremia | Dehydration, lung auscultation with crackles | Acute renal and respiratory failure |
| Temperature (°C) | Not recorded | Not recorded | 36.4 | Not recorded | Not recorded | 36.8 | 36.2 | 38.8 | Not recorded |
| Blood pressure (mmHg) | Not recorded | 130/70 | 187/83 | Not recorded | Not recorded | 180/80 | 166/73 | 160/80 | Not recorded |
| Oxygen saturation (SpO2) | Not recorded | Not recorded | 97% | Not recorded | Not recorded | Not recorded | Not recorded | 97% + 2l O2 | Not recorded |
| SARS-CoV-2 test | No data | No data | Antigen-test: negative PCR-test: negative |
No data | PCR-test: negative | No data | No data | RT-PCR-test: positive (Ct, 20) | No data |
| White-cell count (4–9/nl) | No data | No data | 6.6 | 7.1 | 12.1 | 13.5 | No data | 9.2 | 15.2 |
| Platelet count (140–400/nl) | No data | No data | 267 | 263 | 262 | 254 | No data | 204 | 196 |
| Hemoglobin (14.0–18.0 g/dl) | No data | No data | 7.4 | 7.1 | 7.2 | 8.0 | No data | 8.6 | 9.3 |
| Lactate dehydrogenase (135–250 U/L) | No data | No data | 179 | 165 | No data | No data | No data | No data | 439 |
| Creatinine (0.7–1.2 mg/dl) | No data | No data | 1.91 | 1.78 | No data | 2.04 | No data | 2.17 | 3.23 |
| C-reactive protein (< 0.5 mg/dl) |
No data | No data | 1.0 | 0.8 | No data | 2.0 | No data | No data | 8.8 |
| Sodium (135–145 mmol/l) | No data | No data | 138 | 138 | No data | 154 | 155 | No data | 156 |
RT-PCR, real-time polymerase chain reaction; Ct, cycle threshold.