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. 2021 Apr 16;21:177. doi: 10.1186/s12887-021-02649-5

Table 1.

Demographic data at baseline and anesthesia details

GA group (n = 129) LA group (n = 144) P vaulea
Baseline demographics
 Sex, M/F 63/66 77/67 0.444
 Age at surgery
  <  4 years old 36 22 0.011
  ≥ 4 years old 93 122
 Weight, kg; median (IQR) 17.50 (15.80–18.70) 18.35 (16.50–20.20) < 0.001
 Height, cm; median (IQR) 106.00 (99.50–110.00) 106.00 (101.00–115.00) 0.003
 Past medical history
  Non-recurrent febrile convulsion 2 (2%) 3 (2%) 1.000
  Thalassemia without a history of blood transfusion 3 (2%) 0 0.104
  Favism 0 1 (<1%) 1.000
  Patent ductus arteriosus without treatment 2 (2%) 1 (<1%) 0.604
Pregnancy and birth details
 Preterm (born < 37 weeks’ gestation) 8 (6%) 5 (3%) 0.290
 Birthweight, kg 3.30 (0.53) 3.29 (0.46) 0.909
 One of a multiple pregnancy 2 (2%) 1 (<1%) 0.604
 Abnormal pregnancy examination of mother 4 (3%) 5 (3%) 1.000
 Delivery mode
  Cephalic vaginal 62 (48%) 73 (51%) 0.664
  Cesarean section with intravertebral anesthesia 67 (52%) 71 (49%)
Family demographics
 Maternal age at birth more than 30 years 33 (26%) 45 (31%) 0.302
 Maternal education
  Junior high school 7 (5%) 5 (3%) 0.486
  Senior high school 31 (24%) 27 (19%)
  Bachelor degree 82 (64%) 108 (75%)
  Master degree or higher 9 (7%) 4 (3%)
 Number of children in the family
  1 83 (64%) 92 (64%) 0.909
  2 45 (35%) 50 (35%)
  3 1 (<1%) 2 (1%)
 Birth order
  1 108 (84%) 114 (79%) 0.324
  2 21 (16%) 29 (20%)
  3 0 1 (<1%)
Anaesthesia details
 Duration of surgery, min; median (IQR) 115 (95–140) NA
 Duration of use of sevoflurane, min; median (IQR) 130 (110–160) NA
 Adverse events related to the cardiovascular system 0 1 (<1%)b 1.000
 Adverse events related to the respiratory system 2 (2%)c 0 0.222
 Apparent hypoxiad 0 0

Data are presented as n, means (standard deviations), or median (IQR)

GA General anesthesia, LA Local anesthesia

aPearson’s chi-squared test, Fisher’s exact test, Rank sum test, or Two independent samples t-test

bOne patient had an adverse reaction of local anesthetic with increased heart rate (recovered after treatment)

cTwo children had mild laryngospasm without evident hypoxia during anesthesia recovery

dApparent hypoxia defined as oxygen saturation < 90%