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. 2021 Apr 16;21:123. doi: 10.1186/s12890-021-01491-w

Table 1.

Characteristics of patients with and without pneumococcal pneumonia

Variable and category (reference) Case group
(n = 164)
Control group
(n = 4,054)
p value
Age, yearsa 76.2 ± 7.3 75.1 ± 6.7 0.127
 65–69 32 (19.5) 984 (24.3) 0.153
 70–74 44 (26.8) 1,098 (27.1)
 75–79 36 (22.0) 950 (23.4)
 80 +  56 (34.1) 1,063 (26.2)
Male (vs. female) 113 (68.9) 2,525 (62.3) 0.100
Smoking 0.001
 Non-smokers 37 (22.6) 1,198 (29.6)
 Current smokers 108 (65.9) 2,068 (51.0)
 Ex-smokers 19 (11.6) 788 (19.4)
Chronic respiratory diseases (vs. absent)
 Asthma 30 (18.3) 685 (16.9) 0.671
 COPD 42 (25.6) 959 (23.6) 0.574
 Lung cancer 45 (27.4) 1,594 (39.3) 0.002
 Interstitial pneumonia 29 (17.7) 703 (17.3) 0.916
 NTM 10 (6.1) 449 (11.1) 0.054
 Othersb 48 (29.3) 746 (18.4) 0.001
Diabetes (vs. absent) 65 (39.6) 1,209 (29.8) 0.023
Chronic heart disease (vs. absent) 95 (57.9) 1,891 (46.6) 0.005
Chronic kidney disease (vs. absent) 13 (7.9) 299 (7.4) 0.761
Systemic corticosteroid user (vs. absent) 65 (39.6) 1,189 (29.3) 0.007

Values are expressed as numbers and proportions in parentheses

aMean ± SD

bOther chronic respiratory diseases included chronic pulmonary aspergillosis, old pulmonary tuberculosis, sarcoidosis, and chronic cough

COPD, chronic obstructive pulmonary disease; NTM, non-tuberculous mycobacteriosis