Table 1.
Comparison of variables between Intensive care patients with cancer and without cancer before and after propensity score matched analysis
| Variable | ALL | Patients before PSM | Patients after PSM | ||||||
|---|---|---|---|---|---|---|---|---|---|
| N = 38,508 | Noncancer(N = 30,200) | Cancer (N = 8308) |
P Value | SDD | Noncancer N = 7474 |
Cancer N = 7474 |
P Value | SDD | |
| Age, median (IQR), Y | 65 (52–77) | 63 (50–77) | 70 (60–79) | < 0.001 | 44.2 | 72 (59–81) | 69 (59–79) | 1.000 | −3.3 |
| Sex, No. (%) | 0.545 | 0.8 | 0.921 | 0 | |||||
| Female | 16,715 (43.4) | 13,133 (43.5) | 3582 (43.1) | 3276 (43.8) | 3282 (43.9) | ||||
| Male | 21,783 (56.6) | 17,067 (56.5) | 4726 (56.8) | 4198 (56.2) | 4192 (56.1) | ||||
| Ethnicity, No. (%) | < 0.001 | 11.1 | 0.829 | 1.6 | |||||
| Black | 2949 (7.7) | 2404 (8.0) | 545 (6.6) | 531 (7.1) | 505 (6.8) | ||||
| Asian | 911 (2.4) | 667 (2.2) | 244 (2.9) | 195 (2.6) | 207 (2.8) | ||||
| White | 27,468 (71.3) | 21,035 (69.7) | 6433 (77.4) | 5749 (76.9) | 5735 (76.7) | ||||
| Hispanic | 1254 (3.3) | 1095 (3.6) | 159 (1.9) | 154 (2.1) | 154 (2.1) | ||||
| Other | 5926 (15.4) | 4999 (16.6) | 927 (11.2) | 845 (11.3) | 873 (11.7) | ||||
| ICU type, No. (%) | < 0.001 | 27.7 | 0.717 | 1.7 | |||||
| SICU | 6366 (16.5) | 4578 (15.2) | 1788 (21.5) | 1528 (20.4) | 1499 (20.1) | ||||
| MICU | 13,634 (35.4) | 10,148 (33.6) | 3486 (42.0) | 3090 (41.3) | 3064 (41.0) | ||||
| CCU | 5673 (14.7) | 4728 (16.7) | 945 (11.4) | 906 (12.1) | 920 (12.3) | ||||
| CSRU | 7606 (19.8) | 6378 (21.1) | 1228 (14.8) | 1215 (16.3) | 1207 (16.2) | ||||
| TSICU | 5229 (13.6) | 4368 (14.5) | 861 (10.4) | 735 (9.8) | 784 (10.5) | ||||
| Admission group, No. (%) | < 0.001 | −20.2 | 0.764 | −0.4 | |||||
| Elective | 6090 (15.8) | 4267 (14.1) | 1823 (21.9) | 1465 (19.6) | 1467 (19.6) | ||||
| Emergency | 32,418 (84.2) | 25,993 (85.9) | 6485 (78.1) | 6009 (80.4) | 6007 (80.4) | ||||
| Admission reasons, No. (%) | < 0.001 | −7.0 | 0.860 | 1.4 | |||||
| Cardiovascular | 17,528 (45.5) | 13,726 (45.5) | 3802 (45.8) | 3419 (45.8) | 3416 (45.7) | ||||
| Liver | 1312 (3.4) | 903 (3.0) | 409 (4.9) | 330 (4.4) | 328 (4.4) | ||||
| Mental | 4118 (10.7) | 3300 (10.9) | 818 (9.9) | 783 (10.5) | 771 (10.3) | ||||
| Renal | 4753 (12.3) | 3686 (12.2) | 1067 (12.8) | 1011 (13.6) | 970 (13.0) | ||||
| Respiratory | 6905 (18.0) | 5478 (18.2) | 1427 (17.2) | 1239 (16.6) | 1288 (17.2) | ||||
| Coagulation | 1671 (4.3) | 1257 (4.2) | 414 (5.0) | 366 (4.9) | 356 (4.8) | ||||
| Other | 2221 (5.8) | 1850 (6.1) | 371 (4.5) | 326 (4.4) | 345 (4.6) | ||||
| SOFA, median (IQR) | 3 (2–5) | 3 (2–5) | 3 (2–5) | 0.001 | 2.5 | 3 (2–6) | 3 (2–6) | 0.622 | −0.9 |
| SAPS II, median (IQR) | 24 (33–92) | 31 (23–41) | 39 (26–46) | < 0.001 | 36.6 | 36 (28–46) | 36 (28–44) | 0.490 | −1.4 |
| APS III, median (IQR) | 38 (25–51) | 37 (27–51) | 40 (30–53) | < 0.001 | 11.4 | 40 (29–54) | 39 (30–52) | 0.462 | −2.0 |
| LODS, median (IQR) | 3 (2–5) | 3 (2–5) | 3 (2–5) | < 0.001 | 5.7 | 4 (2–5) | 3 (2–5) | 1.00 | −0.5 |
| OASIS, median (IQR) | 30 (25–37) | 30 (25–37) | 30 (25–37) | 0.293 | 1.2 | 31 (25–37) | 31 (25–37) | 0.09 | −1.4 |
| Elixhause comorbidity, median (IQR) | 4 (0–12) | 3 (0–9) | 9 (2–17) | < 0.001 | 56.0 | 9 (0–16) | 8 (0–15) | 0.933 | −0.4 |
| RRT on first day, No. (%) | 1036 (2.7) | 889 (2.9) | 147 (1.8) | < 0.001 | −7.7 | 154 (2.1) | 145 (1.9) | 0.599 | −0.7 |
| MV on first day, No. (%) | 17,613 (45.7) | 14,262 (47.2) | 3351 (40.3) | < 0.001 | −13.9 | 3051 (40.8) | 3084 (41.3) | 0.583 | 1.1 |
| Vasopressor administration on first day, No. (%) | 11,354 (29.5) | 9114 (30.2) | 2240 (27.0) | < 0.001 | −7.1 | 2094 (28.0) | 2076 (27.8) | 0.743 | −1.1 |
| Sepsis, No. (%) | 2601 (6.8) | 1951 (6.5) | 650 (7.8) | < 0.001 | 5.3 | 603 (8.1) | 783 (7.8) | 0.545 | −1.4 |
| Infection, No. (%) | 15,192 (39.5) | 11,641 (38.6) | 3551 (42.7) | < 0.001 | 8.5 | 3164 (42.3) | 2196 (42.8) | 0.597 | 1.1 |
Abbreviations: ICU Intensive care unit; SDD The standardized differences; PSM Propensity score matching; IQR 25–75% Interquartile range; SOFA Sequential Organ Failure Assessment; SAPSII Simplified Acute Physiology Score II; LODS Logistic Organ Dysfunction Score; OASIS Oxford Acute Severity of Illness Score; APSIII Acute Physiology Score; SICU Surgical intensive care unit; MICU Medical intensive care unit; CCU Coronary care unit; CSRU Cardiac surgery recovery unit; TSICU Traumatic surgical intensive care unit; MV Mechanical ventilation; RRT Renal replacement therapy