Table 2.
Gene ontology term enrichment
| GHFT1 cells | TαT1 cells | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | Structure and development1 | Expression | Gene | Synapse development and function2 | Expression | ||||||||||
| A | B | C | D | E | GHFT1 | TαT1 | F | G | H | I | J | GHFT1 | TαT1 | ||
| Cyr61 | X | X | X | X | X | 117.1 | 0.5 | Nrxn1 | X | X | X | X | X | 0.0 | 4.2 |
| Edn1 | X | X | X | X | X | 7.3 | 0.0 | Unc13a | X | X | X | X | X | 0.0 | 19.8 |
| Bmp4 | X | X | X | X | X | 6.8 | 0.0 | Drd2 | X | X | X | X | 0.0 | 12.4 | |
| Tgfbr2 | X | X | X | X | X | 65.1 | 0.0 | Chrnb2 | X | X | X | X | 0.0 | 12.7 | |
| Fgf10 | X | X | X | X | X | 1.1 | 0.0 | Grin1 | X | X | X | X | 0.0 | 20.5 | |
| Gli3 | X | X | X | X | X | 13.4 | 0.0 | Syt4 | X | X | X | X | 0.0 | 86.3 | |
| Mef2c | X | X | X | X | X | 7.6 | 0.0 | Grin3a | X | X | X | X | 0.0 | 11.4 | |
| Cav1 | X | X | X | X | X | 10.1 | 0.0 | Snap25 | X | X | X | X | 0.1 | 107.4 | |
| Bmp5 | X | X | X | X | X | 3.8 | 0.0 | Sez6 | X | X | X | X | X | 0.0 | 39.8 |
| Ctgf | X | X | X | X | X | 40.3 | 0.0 | Gabrg2 | X | X | X | X | X | 0.0 | 13.0 |
| Gli2 | X | X | X | X | X | 4.2 | 0.0 | Pclo | X | X | X | X | X | 0.0 | 4.0 |
| Gata6 | X | X | X | X | X | 1.2 | 0.0 | Atp2b2 | X | X | 0.0 | 9.4 | |||
| Tbx20 | X | X | X | X | X | 2.2 | 0.0 | Chrna4 | X | X | X | 0.0 | 3.4 | ||
| Msx2 | X | X | X | X | X | 20.1 | 0.0 | Shisa6 | X | X | X | 0.0 | 11.3 | ||
| Yap1 | X | X | X | X | X | 40.3 | 0.2 | Lrrc4c | X | X | 0.0 | 1.7 | |||
| Sfrp1 | X | X | X | X | X | 7.1 | 0.0 | Thy1 | X | 0.0 | 23.3 | ||||
| Hlx | X | X | X | X | X | 1.5 | 0.0 | Glra3 | X | X | X | X | 0.0 | 28.1 | |
| Cxcl12 | X | X | X | X | X | 4.2 | 0.0 | Adgfb1 | X | X | 0.0 | 9.5 | |||
| Pax3 | X | X | X | X | X | 9.1 | 0.0 | Gria1 | X | X | X | 0.0 | 11.7 | ||
| Fn1 | X | X | X | X | X | 611.8 | 1.0 | Lgi1 | X | 0.0 | 1.1 | ||||
1 The top five GO terms associated with the top 5% of the most differentially expressed genes (log 2-fold-change) in GHFT1 cells are A = animal organ development, B = anatomical structure development, C = anatomical structure morphogenesis, D = multicellular organism development, E = system development. X’s illustrate the association of each gene with a GO term. Expression is given in FPKM
2 The top five GO terms associated with TαT1 cells are: F = synaptic signaling, G = trans-synaptic signaling, H = synapse organization, I = nervous system development, J = anterograde trans-synaptic signaling