Table 2.
Results of determination of the active ingredient content, disintegration time, and compressibility index in different formulations. Values are expressed as mean±SD (n=3)
| Formulation Code | Drug content (%)±SD | Disintegration time (min)±SD | Compressibility index (%)±SD |
Angle of repose
(Degree)±SD |
Hausner's ratio±SD |
Drug release
% in 25 minute ±SD |
|---|---|---|---|---|---|---|
| F1 | 90.66±1.09 | 20.03±0.03 | 19.51±0.05 | 33.39±0.06 | 1.24±0.04 | 75.76±2.68 |
| F2 | 86.75±0.90 | 19.11±0.01 | 13.69±0.06 | 37.83±0.08 | 1.15±0.05 | 75.50±2.03 |
| F3 | 87.39±1.68 | 16.30±0.01 | 14.28±0.09 | 33.80±0.08 | 1.16±0.08 | 75.15±1.32 |
| F4 | 86.90±0.77 | 19.25±0.02 | 18.18±0.11 | 33.88±0.06 | 1.22±0.10 | 78.34±0.88 |
| F5 | 88.29±0.79 | 12.04±0.03 | 18.18±0.07 | 35.36±0.12 | 1.22±0.07 | 78.72±0.95 |
| F6 | 91.20±0.49 | 16.14±0.03 | 14.28±0.09 | 37.17±0.05 | 1.16±0.08 | 79.42±1.64 |
| F7 | 91.36±0.82 | 13.60±0.07 | 9.09±0.05 | 29.65±0.10 | 1.10±0.04 | 81.91±1.07 |
| F8 | 91.53±0.45 | 9.51±0.05 | 7.93±0.06 | 29.20±0.08 | 1.08±0.06 | 82.51±0.81 |
| F9 | 91.69±0.33 | 9.36±0.02 | 7.93±0.04 | 27.43±0.06 | 1.08±0.04 | 83.02±0.81 |