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Impact of leukocyte activation on blood flow and rheology in the microcirculation. In ischemia-reperfusion, peripheral resistance is elevated due to leukocyte obstruction due to pseudopod projections or cell adhesion to the vascular wall. (a) Normal Blood Flow. (b) Vessel during ischemia-reperfusion. (c) Vessel during ischemia reperfusion, treated with nitric oxide.
